Table 3.

Postnatal exposure to medical diagnostic radiation and risk estimates of childhood and adolescent brain tumors

1-year latency perioda2-years latency periodb5-years latency perioda
CasesControlsAdjusted ORc (95% CI)CasesControlsAdjusted ORc (95% CI)CasesControlsAdjusted ORc (95% CI)
X-ray or scan
 Yes1823620.86 (0.65–1.14)1593330.76 (0.58–1.01)1152460.81 (0.60–1.08)
 No1682821 (ref)1913111 (ref)2353981 (ref)
 Missing2222
No. of X-ray or scan
 No X-ray or scan1682821 (ref)1913111 (ref)2353981 (ref)
 1871740.84 (0.60–1.18)811690.75 (0.54–1.06)661360.82 (0.58–1.15)
 238770.85 (0.54–1.34)34700.78 (0.48–1.25)24580.72 (0.43–1.19)
 3 or more571110.90 (0.60–1.35)44940.78 (0.51–1.21)25520.81 (0.49–1.36)
X-ray or scan (head or body+head)
 Yes47801.19 (0.78–1.80)41761.09 (0.71–1.67)28550.97 (0.60–1.57)
 No3035641 (ref)3095681 (ref)3225891 (ref)
X-ray (head or body+head)
 Yes21470.97 (0.53–1.80)18440.85 (0.45–1.60)13340.82 (0.40–1.69)
 No X-ray or scan to the head3045701 (ref)3105741 (ref)3235921 (ref)
CT (head or body+head)
 Yes16141.95 (0.90–4.22)14131.86 (0.82–4.22)10101.68 (0.69–4.09)
 No X-ray or scan to the head3045711 (ref)3105751 (ref)3235931 (ref)
MRI (head or body+head)
 Yes7101.75 (0.60–5.11)5101.25 (0.38–4.05)250.93 (0.17–5.21)
 No X-ray or scan to the head3045701 (ref)3105741 (ref)3235921 (ref)
Ultrasound (head or body+head)
 Yes5100.80 (0.23–2.79)4100.79 (0.22–2.76)290.47 (0.09–2.32)
 No X-ray or scan to the head3045701 (ref)3105741 (ref)3235921 (ref)
  • NOTE: Medical diagnostic examinations that were performed during the latency period were not taken into account.

  • aSensitivity analysis.

  • bMain analyses.

  • cConditional logistic regression models adjusted for highest parental education, maternal age, and paternal age.