Table 3.

Proportional hazards models for risk of death

Adjusted estimates
Full modelReduced model
HRAdj (CI)PHRAdj (CI)P
PMAa0.98 (0.96–0.99)0.0440.97 (0.96–0.99)0.002
Age:1.01 (0.99–1.03)0.297
Sex:
 Male1.65 (1.11–2.46)0.0141.80 (1.24–2.63)0.002
 FemaleRefRef
Smoking
 NeverRef
 Former0.85 (0.49–1.43)
 Current0.84 (0.48–1.44)0.797
Chronic bronchitis1.09 (0.66–1.80)0.745
Emphysema1.51 (0.98–2.33)0.0641.51 (0.98–2.19)0.070
Histology:
 AdenocarcinomaRefRef
 Squamous cell0.82 (0.50–1.36)0.83 (0.50–1.36)0.451
 Large cell0.66 (0.36–1.21)0.64 (0.35–1.17)0.147
 NSCLC (NOS/mixed)0.62 (0.41–0.94)0.1210.61 (0.41–0.94)0.113
Stage
 IRefRef
 II1.72 (0.52–5.65)1.46 (0.45–4.73)
 III4.05 (1.56–10.5)3.46 (1.36–8.81)
 IV7.32 (3.07–17.4)<0.0016.28 (2.69–14.7)<0.001
Radiation1.03 (0.59–1.79)0.915
Chemotherapy0.73 (0.37–1.41)0.344
Surgery0.57 (0.37–0.87)0.0100.59 (0.39–0.90)0.015
ECOG performance
 Status 0–2RefRef
 Status 3–42.01 (0.95–4.25)0.0702.15 (1.03–4.446)0.101
BMI0.98 (0.94–1.02)0.262
  • NOTE: For chronic bronchitis and emphysema, references are “no chronic bronchitis” and “no emphysema,” respectively. For radiation, chemotherapy, and surgery, references are “no radiation,” “no chemotherapy,” and “no surgery,” respectively.

  • Abbreviation: NOS, not otherwise specified.

  • aPer 1 cm2 increase in PMA.