Table 1.

Characteristics by category of weight change in the KPNC population of breast cancer patients diagnosed from 2005 to 2013 (N = 12,590)

Large loss (≥10%)Modest loss (>5%–<10%)Stable (within 5%)Modest gain (>5%–<10%)Large gain (≥10%)Total
N8271,5367,8361,64574612,590
Mean or median
Median (range) of follow-up, years3 (0–9)3 (0–9)3 (0–9)3 (0–9)4 (0–8)3.4 (0–9)
Median age at diagnosis, years616060565459
Median change (pounds)−28−120.1011240
Percent
History of alcohol drinking
 Never474945424645
 Former323222
 Current504952565152
History of smoking
 Never555759546160
 Former353330303031
 Current1010111689
Diagnosis BMI category
 Obese544735282237
 Overweight282931333431
 Normal weight182433384032
 Underweight0.111231
Race/Ethnicity
 White716864686866
 Black11777107
 Hispanic8111091110
 Asian111418151016
 Other011111
Comorbidities, yes/no18161211913
Tumor stage
 I455058575855
 II393733353335
 III161398910
Breast cancer subtypea
 Surrogate Luminal A434848474347
 Surrogate Luminal B373436363836
 Her2+, endocrine negative655545
 Triple negative141311121412
Chemotherapy545243475546
Radiotherapy344043423442
  • aDefinitions adapted by Prat and colleagues (18) from the 3-marker IHC plus grade subtypes in the St. Gallen's Consensus Conference; we separated breast cancer into subtypes as follows: (i) surrogate Luminal A (well or moderately differentiated and ER+ and PR+ and Her2); (ii) surrogate Luminal B (poorly or undifferentiated ER+ or PR+ and any of PR, Her2+); (iii) HER2-positive, endocrine negative (ER, PR, and Her2+); and (iv) triple negative (ER, PR, and Her2).