Table 3.

Adjusted ORs for the associations between talc use and serous/nonserous EOC

Histologic subtypeaCasesControlsORb (95% CI)
n (%)n (%)
Serous (n = 392)
 Never use156 (39.8)351 (47.1)1.00 (Referent)
 Only nongenital use71 (18.1)140 (18.8)1.10 (0.76–1.58)
 Any genital use165 (42.1)254 (34.1)1.38 (1.03–1.85)
Nonserous (n = 144)
 Never use44 (30.6)351 (47.1)1.00 (Referent)
 Only nongenital use42 (29.2)140 (18.8)2.28 (1.39–3.74)
 Any genital use58 (40.3)254 (34.1)1.63 (1.04–2.55)
  • aTest for interaction for association with powder use by serous and nonserous histologic subtype and route of body powder exposure was P = 0.008 for “only” nongenital powder use and P = 0.50 for “any” genital powder use.

  • bAdjusted for age at diagnosis/interview, study site, education, tubal ligation, parity, BMI, duration of OC use, first-degree family history of breast or ovarian cancer, and interview year.