Table 1.

Characteristics of cohorts included in database (as of August 19, 2015)a

CohortYearCurrentlyMost recentEnrollmentParticipant ages
Cohort namebAbbreviationdesign typebenrollment beganenrolling (Y/N)year data collectedMaleFemaleMinimumMaximumWebsite
Agricultural Health StudyAHSRisk1993N201455,96733,6893064Yes
Seventh-day Adventist Cohort Study-2AHS-2Risk2002N201533,64362,31130111Yes
Alpha-Tocopherol Beta-Carotene Cancer Prevention StudyATBCRisk1985N199329,133N/A5069Yes
British Columbia Generations ProjectBC GenerationsHybrid2009Y20159,29820,3063569Yes
Breast Cancer Family Registry CohortBCFR CohortHybrid1992N20146,09430,12615101Yes
Breast Cancer Surveillance Consortium Research ResourceBCSCRisk1994N2009N/A2,326,13218109Yes
Breakthrough Generations StudyBGSRisk2003NRa2015N/A113,00016102Yes
A Follow-up Study for Causes of Cancer in Black Women: Black Women's Health StudyBWHSRisk1995Y2013N/A59,0002169Yes
Carotene and Retinol Efficacy TrialCARETRisk1985N200512,0256,2894574Yes
CARTaGENECARTaGENEHybrid2008N201519,25022,9924069Yes
Clue Cohort Study- Clue ICLUE IRisk1974N197410,95215,1931297Yes
Clue Cohort Study- Clue IICLUE IIRisk1989N200714,17118,723299Yes
Colon Cancer Family Registry CohortColon CFRHybrid1997N201516,86220,6981875Yes
Cancer Prevention Study II Nutrition CohortCPS-II NutritionRisk1992N201386,40297,7834093Yes
Canadian Study of Diet, Lifestyle and HealthCSDLHRisk1992N199934,29139,61821100+No
California Teachers StudyCTSRisk1995N2014N/A133,47922104Yes
European Prospective Investigation in Cancer and NutritionEPICRisk1992N2015153,457366,5213570Yes
Golestan Cohort StudyGCSRisk2004N201221,23428,8114075Yes
Health Professionals Follow-up StudyHPFSRisk1986N201451,529N/A4075Yes
Iowa Women's Health StudyIWHSRisk1986N2004N/A41,8365569Yes
Janus Serum BankJanusRisk1972N2004166,137152,4911868Yes
Mexican American (Mano a Mano) CohortMACHybrid2001Y20145,54018,8981894Yes
The Melbourne Collaborative Cohort StudyMCCSRisk1990N200717,04524,4692776Yes
Multiethnic CohortMECRisk1993N201596,810118,4414575Yes
Mayo Mammography Health StudyMMHSRisk2003N2006N/A17,6393594Yes
Nurses' Health StudyNHSRisk1976N2014N/A121,7013055Yes
Nurses' Health Study IINHSIIRisk1989N2013N/A116,4302542Yes
The National Institutes of Health AARP Diet and Health StudyNIH-AARPRisk1995N2006339,666226,7325071Yes
NYU Women's Health StudyNYUWHSRisk1985N2010N/A14,2743565Yes
Ontario Health StudyOHSHybrid2010Y201584,505127,2271899Yes
Prostate Cancer Prevention TrialPCPTRisk1994N200118,880N/A5586Yes
Physicians' Health Study I and IIPHS I & IIRisk1982N201429,071N/A4088Yes
Prostate, Lung, Colorectal and Ovarian Cancer Screening TrialPLCORisk1993N201475,52173,1615574Yes
RERF Life Span Study (Adult Health Study Clinical Subcohort) & F1 Cohort (Hiroshima and Nagasaki)RERFRisk1950N201050,17570,1460>60Yes
Southern Community Cohort StudySCCSRisk2002N201534,20350,3664079Yes
Singapore Chinese Health StudySCHSRisk1993Y201327,95435,3034574No
Shanghai Cohort StudySCSRisk1986Y201318,244N/A4564No
Selenium and Vitamin E Cancer Prevention TrialSELECTRisk2001N201434,897N/A5093Yes
Sister StudySISRisk2003N2014N/A50,8843574Yes
Shanghai Men's Health StudySMHSRisk2001N201461,491N/A4074Yes
Shanghai Women's Health StudySWHSRisk1997N2014N/A74,9414070Yes
VITamins And LifestyleVITALRisk2000N200237,39340,3455076Yes
Women's Health InitiativeWHIRisk1994N2014N/A161,8085079Yes
Women's Health Initiative Cancer Survivor CohortWHI-CSCSurvivor2013N2013N/A8,9925094Yes
Women's Health StudyWHSRisk1992N2014N/A39,8763990Yes
Women's Lifestyle and HealthWLHHybrid1991N2003N/A49,2583050Yes
  • Abbreviations: N/A, not applicable; cohort not enrolling gender; NR, not reported.

  • aData retrieved from The Cancer Epidemiology Descriptive Cohort Database. The Epidemiology and Genomics Research Program. NCI (https://cedcd.nci.nih.gov; updated July 6, 2015; accessed December 17, 2015).

  • bCohort design types defined as follows: Risk epidemiology cohort is defined as a cohort enrolling healthy participants and follows them over time to see whether they acquire a disease/outcome; Survivor cohort is defined as a cohort enrolling participants diagnosed with cancer and follows them over time; Hybrid cohort is defined as a cohort that enrolls both healthy individuals and cancer survivors and follows them over time