Table 2.

Prevalence of HPV16, other HR-HPV types not including HPV16 (HR other), and LR-HPV only (LR-only) in all combinations of results obtained by cytology and histology in 605 men with complete baseline results on cytology, histology, and HPV in the Study of the Prevention of Anal Cancer

Histology
Negative/normalLSILHSIL-AIN2HSIL-AIN3Total
Cytologyn (%)n (%)n (%)n (%)N (%)
Unsatisfactory
n1580427
 Negative4 (26.7)1 (12.5)0 (0.0)0 (0.0)5 (18.5)
 HPV162 (13.3)2 (25.0)0 (0.0)3 (75.0)7 (25.9)
 HR other5 (33.3)3 (37.5)0 (0.0)1 (25.0)9 (33.3)
 LR only4 (26.7)2 (25.0)0 (0.0)0 (0.0)6 (22.2)
 Total HPV11 (73.3)7 (87.5)0 (0.0)4 (100.0)22 (81.5)
Negative
n166401417237
 Negative51 (30.7)6 (15.0)1 (7.1)0 (0.0)58 (24.5)
 HPV1620 (12.0)3 (7.5)1 (7.1)7 (41.2)31 (13.1)
 HR other45 (27.1)12 (30.0)9 (64.3)7 (41.2)73 (30.8)
 LR only50 (30.1)19 (47.5)3 (21.4)3 (17.6)75 (31.6)
 Total HPV115 (69.3)34 (85.0)13 (92.9)17 (100.0)179 (75.5)
ASCUS
n3439919101
 Negative5 (14.7)4 (10.3)0 (0.0)1 (5.3)10 (9.9)
 HPV167 (20.6)9 (23.1)1 (11.1)9 (47.4)26 (25.7)
 HR other16 (47.1)13 (33.3)7 (77.8)7 (36.8)43 (42.6)
 LR only6 (17.6)13 (33.3)1 (11.1)2 (10.5)22 (21.8)
 Total HPV29 (85.3)35 (89.7)9 (100.0)18 (94.7)91 (90.1)
LSIL
n6246945
 Negative0 (0.0)1 (4.2)0 (0.0)0 (0.0)1 (2.2)
 HPV160 (0.0)7 (29.2)2 (33.3)5 (55.6)14 (31.1)
 HR other4 (66.7)11 (45.8)3 (50.0)4 (44.4)22 (48.9)
 LR only2 (33.3)5 (20.8)1 (16.7)0 (0.0)8 (17.8)
 Total HPV6 (100.0)23 (95.8)6 (100.0)9 (100.0)44 (97.8)
ASC-H
n252093387
 Negative1 (4.0)1 (5.0)0 (0.0)0 (0.0)2 (2.3)
 HPV169 (36.0)5 (25.0)3 (33.3)19 (57.6)36 (41.4)
 HR other10 (40.0)9 (45.0)6 (66.7)11 (33.3)36 (41.4)
 LR only5 (20.0)5 (25.0)0 (0.0)3 (9.1)13 (14.9)
 Total HPV24 (96.0)19 (95.0)9 (100.0)33 (100.0)85 (97.7)
HSIL-AIN2
n553821
 Negative0 (0.0)0 (0.0)1 (33.3)0 (0.0)1 (4.8)
 HPV162 (40.0)1 (20.0)1 (33.3)5 (62.5)9 (42.9)
 HR other3 (60.0)2 (40.0)1 (33.3)3 (37.5)9 (42.9)
 LR only0 (0.0)2 (40.0)0 (0.0)0 (0.0)2 (9.5)
 Total HPV5 (100.0)5 (100.0)2 (66.7)8 (100.0)20 (95.2)
HSIL-AIN3
n121485387
 Negative0 (0.0)1 (7.1)0 (0.0)2 (3.8)3 (3.4)
 HPV166 (50.0)7 (50.0)4 (50.0)38 (71.7)55 (63.2)
 HR other5 (41.7)5 (35.7)3 (37.5)12 (22.6)25 (28.7)
 LR only1 (8.3)1 (7.1)1 (12.5)1 (1.9)4 (4.6)
 Total HPV12 (100.0)13 (92.9)8 (100.0)51 (96.2)84 (96.6)
Total
n26315049143605
 Negative61 (23.2)14 (9.3)2 (4.1)3 (2.1)80 (13.2)
 HPV1646 (17.5)34 (22.7)12 (24.5)86 (60.1)178 (29.4)
 HR other88 (33.5)55 (36.7)29 (59.2)45 (31.5)217 (35.9)
 LR only68 (25.9)47 (31.3)6 (12.2)9 (6.3)130 (21.5)
 Total HPV202 (76.8)136 (90.7)47 (95.9)140 (97.9)525 (86.8)