Table 1.

Baseline characteristics of the SHAPE-2 study population

Control group (n = 48)Diet group (n = 97)Mainly exercise group (n = 98)
Mean (SD)
Age (years)60.0 (4.9)60.5 (4.6)59.5 (4.9)
Time since last menses (years)11.4 (7.8)10.7 (6.1)10.9 (7.7)
Educationa, number (%)
 Low15 (31.3%)27 (27.8%)33 (33.6%)
 Middle15 (31.3%)27 (27.8%)20 (20.4%)
 High18 (37.5%)42 (43.3%)44 (44.9%)
First-degree family member with breast cancer, number (%)9 (18.8%)23 (23.7%)24 (24.5%)
Weight (kg)80.9 (10.0)80.0 (8.6)80.4 (9.0)
BMI (kg/m2)29.5 (2.6)29.3 (2.5)29.0 (2.9)
Body fat percentage (%)43.6 (5.0)44.1 (3.8)43.8 (4.0)
Total body fat (kg)34.2 (7.4)33.9 (5.7)33.9 (6.2)
Lean mass (kg)43.4 (3.9)42.7 (4.0)43.1 (4.1)
VO2peak, relative (mL/kg/min)22.1 ± 4.721.9 ± 4.021.8 ± 3.7
VO2peak (mL/min)1,751 ± 3631,742 ± 3101,749 ± 293
Physical activity, activity monitorb (min/day)Median (interquartile range)
 Sedentary652 (600–691)637 (606–685)630 (593–678)
 Light179 (164–226)194 (175–214)197 (157–229)
 Moderate35 (25–39)35 (22–46)33 (27–46)
 Vigorous0.33 (0.17–0.61)0.35 (0.17–0.53)0.29 (0.14–0.47)
SQUASH questionnaire, moderate and vigorous activityc (min/week)270 (120–495)184 (115–420)248 (90–465)
Alcohol (g/day)3.7 (0.0–11.7)5.7 (0.0–10.0)4.3 (0.0–10.0)
Geometric mean (95% CI)
hsCRP (mg/L)1.83 (1.40–2.40)2.04 (1.67–2.49)1.81 (1.49–2.19)
IL6 (pg/mL)1.31 (1.12–1.52)1.41 (1.27–1.55)1.41 (1.25–1.59)
Adiponectin (ng/mL)9.34 (8.38–10.41)9.68 (9.06–10.34)9.53 (9.10–9.99)
Leptin (ng/mL)27.4 (23.1–32.5)28.5 (25.5–32.0)31.4 (28.1–35.2)
  • NOTE: Data on family history of breast cancer were available for n = 241 (99.2%) women; DEXA scan (body fat mass, lean mass), n = 240 (98.8%); VO2peak, n = 237 (97.5%); alcohol intake, n = 226 (93.0%); accelerometer data, n = 161 of 215 women in total (74.9%); SQUASH questionnaire, n = 236 (97.1%); blood samples for risk markers, n = 242. All other data were available for all 243 women.

  • aEducation: low, primary school and technical/professional school; middle, college degree; high, university degree.

  • bGT3X+ ActiGraph activity monitor. Minutes/day of activity spent in each activity category.

  • cActivities performed ≥4 metabolic equivalents (MET).