Table 1.

Clinical features in EOC cases and controls included in the GE and BMI-GE analyses

CharacteristicsControls: N (%)Cases: N (%)P
Age (years)<0.0001
 Mean ± SD57.5 ± 11.658.3 (11.0)
Age (categorical)<0.0001
 <50 years2,604 (25.1)1,366 (21.9)
 50–55 years1,424 (13.7)946 (15.1)
 55–60 years1,691 (16.3)1,071 (17.1)
 60–65 years1,629 (15.7)1,015 (16.2)
 >65 years3,031 (29.2)1,849 (29.6)
Young adult BMI (kg/m2)<0.0001
 Underweight/normal (<25)7,607 (91.8)4,427 (89.7)
 Overweight/obese (>25)679 (8.2)508 (10.3)
Parity<0.0001
 0 full births1,415 (14.7)1,453 (25.1)
 >0 full births8,234 (85.3)4,328 (74.9)
Breast feed<0.0001
 No2,312 (30.3)1,641 (39.9)
 Yes5,320 (69.7)2,467 (60.1)
Oral contraceptive use<0.0001
 (≤2 years)4,895 (47.4)3,487 (57.1)
 (>2 years)5,428 (52.6)2,616 (42.9)
Estrogen use0.44
 No3,986 (78.9)2,250 (78.1)
 Yes1,068 (21.1)631 (21.9)
EPP MHT use<0.0001
 No3,420 (67.7)2,105 (73.3)
 Yes1,631 (32.3)765 (26.7)
Endometriosis<0.0001
 No8,738 (93.9)4,802 (90.0)
 Yes568 (6.1)533 (10.0)
Tubal ligation<0.0001
 No6,924 (77.8)4,692 (83.5)
 Yes1,976 (22.2)926 (16.5)
Tumor grade
 Well-differentiated739 (12.1)
 Moderately differentiated1,358 (22.2)
 Poorly differentiated2,911 (47.6)
 Undifferentiated459 (7.5)
 Other647 (10.6)
Histotypes
 Serous3,589 (57.4)
 Mucinous403 (6.5)
 Endometrioid961 (15.4)
 Clear cell468 (7.5)
 Others827 (13.2)

NOTE: Sample sizes vary as not all studies collected data on each lifestyle and reproductive factor.