Table 1.

Demographic and health characteristics controls and ovarian cancer cases by histologic subtype, nested case–control study within the WHI-OS

ControlsOvarian cancer casesSerousNonserous
n = 412n = 169n = 102n = 67
CharacteristicsMean (SD)Mean (SD)Mean (SD)Mean (SD)
Age64.3 (7.2)64.1 (7.2)64.7 (7.2)63.2 (7.1)
Year of blood drawna (%)na (%)na (%)na (%)
 1993–1996254 (61.7)108 (63.9)62 (60.8)46 (68.7)
 1997–1998158 (38.3)61 (36.1)40 (39.2)21 (31.3)
Race/ethnicity
 White371 (90.0)151 (89.3)96 (94.1)55 (82.1)
 Black17 (4.1)8 (4.7)3 (2.9)5 (7.5)
 Hispanic12 (2.9)6 (3.6)2 (2.0)4 (6.0)
 Other12 (2.9)4 (2.4)1 (1.0)3 (4.5)
Hysterectomy (baseline or follow-up prior to event)
 No340 (82.5)140 (82.8)83 (81.4)57 (85.1)
 Yes72 (17.5)29 (17.2)19 (18.6)10 (14.9)
Time since last menopausal hormone therapy use
 >1 year400 (97.1)163 (96.4)97 (95.1)66 (98.5)
 ≤1 year12 (2.9)6 (3.6)5 (4.9)1 (1.5)
Family income
 <$35,000161 (39.1)69 (40.8)41 (40.2)28 (41.8)
 $35,000–$74,999153 (37.1)65 (38.5)40 (39.2)25 (37.3)
 $75,000+65 (15.8)24 (14.2)16 (15.7)8 (11.9)
Smoking status
 Never203 (49.3)81 (47.9)51 (50.0)30 (44.8)
 Former168 (40.8)76 (45.0)43 (42.2)33 (49.3)
 Current38 (9.2)12 (7.1)8 (7.8)4 (6.0)
BMI (kg/m2)
 <25181 (43.9)66 (39.1)43 (42.2)23 (34.3)
 25–29.9127 (30.8)52 (30.8)31 (30.4)21 (31.3)
 30+103 (25.0)51 (30.2)28 (27.5)23 (34.3)
Age at menarche
 <12100 (24.3)37 (21.9)24 (23.5)13 (19.4)
 12–13220 (53.4)100 (59.2)59 (57.8)41 (61.2)
 14+89 (21.6)32 (18.9)19 (18.6)13 (19.4)
Ever pregnant
 No54 (13.1)25 (14.8)13 (12.7)12 (17.9)
 Yes358 (86.9)144 (85.2)89 (87.3)55 (82.1)
Duration oral contraceptive use
 Never254 (61.7)106 (62.7)65 (63.7)41 (61.2)
 <5 years84 (20.4)36 (21.3)23 (22.5)13 (19.4)
 5–<10 years39 (9.5)14 (8.3)5 (4.9)9 (13.4)
 10+ years35 (8.5)13 (7.7)9 (8.8)4 (6.0)
Age at menopause
 <4017 (4.1)4 (2.4)3 (2.9)1 (1.5)
 40–4433 (8.0)14 (8.3)11 (10.8)3 (4.5)
 45–4991 (22.1)34 (20.1)18 (17.6)16 (23.9)
 50–54183 (44.4)83 (49.1)52 (51.0)31 (46.3)
 55+66 (16.0)22 (13.0)14 (13.7)8 (11.9)
Menopausal hormone therapy use
 Never242 (58.7)129 (76.3)74 (72.5)55 (82.1)
 Former170 (41.3)40 (23.7)28 (27.5)12 (17.9)
  • aValues may not sum to total because of missing data.