Table 1.

Baseline characteristics of composite REVEAL-TLCN cohort

Cases (HCC; n = 602)Controls (non-HCC;n = 3,222)P
Age (years)
 30–3997 (16)1,129 (35)<.001
 40–49169 (28)921 (29)
 50–59196 (33)886 (28)
 >60132 (22)286 (9)
Gender
 Female179 (30)1,322 (41)<.001
 Male415 (70)1,900 (59)
ALT (U/L)
 <45388 (64)3,064 (95)<.001
 >45214 (36)158 (5)
HBV DNA level (copies/mL)
 <30036 (6)782 (26)<.001
 300–9,99999 (17)1,003 (33)
 10,000–999,999247 (42)819 (27)
 >1 million200 (34)454 (15)
Alcohol drinking
 No424 (72)2,854 (89)<.001
 Yes167 (28)363 (11)
rs1229984 (ADH1B)
 CC48 (8)236 (7)<.001
 CT262 (44)1,229 (38)
 TT283 (47)1,748 (54)
rs671 (ALDH2)
 GG303 (50)1,617 (50)0.11
 GA248 (41)1,354 (42)
 AA49 (8)250 (8)

Abbreviation: HCC, hepatocellular carcinoma.