Table 2.

Invasive cancer IRsa by primary site, Appalachian Region and US non-Appalachiab, males and females, all races, 2004–2011

Southern AppalachiaCentral AppalachiaNorthern AppalachiaAll AppalachiaUS non-Appalachia
Males rateFemales rateMales rateFemales rateMales rateFemales rateMales rateFemales rateMales rateFemalesrate
All sites568.7c402.3c561.6c427.2c567.1c449.3c565.8c428.7c543.0418.2
Oral cavity and pharynx18.9c6.6c18.0c6.416.76.317.8c6.4c16.56.2
Esophagus8.0c1.6c8.61.6c10.0g1.99.0c1.7c8.51.9
Stomach8.7c4.4c8.1c3.9c10.0c4.2c9.0c4.2c9.54.7
Colon and rectum55.0c39.155.5c41.0c58.0c43.8c56.6c41.8c52.439.5
Liver and intrahepatic bile duct9.2c2.9c8.0c2.7c8.2c2.6c8.4c2.8c10.73.6
Pancreas13.710.2c12.8c9.5c14.2c11.0c13.610.3c13.710.7
Larynx8.5c1.9c8.8c2.3c7.4c1.7c8.2c2.0c6.61.4
Lung and bronchus101.9c56.5c110.4c67.0c89.4c58.2c100.4c61.0c79.554.7
Melanoma of the skin (whites)31.8c22.6c28.9c19.8c21.3c15.9c27.419.1c27.417.8
Breast145.5c138.4c151.3c145.2c153.0
 Invasive117.3c115.0c121.5118.2c122.4
In situ28.2c23.4c29.7c27.0c30.5
Cervix uteri8.28.8c7.98.3c7.9
Corpus and uterus, NOS18.8c24.531.1c25.2c24.5
Ovary12.412.413.4c12.7c12.3
Prostate150.6c130.2c142.6c139.9c147.0
Testis4.5c5.36.7c5.55.5
Urinary bladder34.5c7.8c37.7c9.445.4c11.3c39.8c9.7c37.09.3
Kidney and renal pelvis21.211.121.8c11.9c20.811.8c21.211.7c21.111.0
Brain and other nervous system8.05.98.3c6.1c8.4c6.1c8.3c6.1c7.95.7
Thyroid5.0c14.6c5.917.47.7g25.5c6.3c19.2c6.017.7
Hodgkin Lymphoma3.02.2c2.9c2.33.6c2.9c3.12.53.22.5
Non-Hodgkin lymphoma21.5c14.9c23.116.224.6c17.7c23.316.423.416.3
Myeloma7.64.97.24.5c7.1c4.6c7.3c4.7c7.54.9
Leukemia16.0c9.8c16.910.317.6c10.9c16.910.4c16.710.2

Abbreviation: NOS, not otherwise specified.

  • aRates are per 100,000 persons age-adjusted to the 2000 US standard population.

  • bSouthern Appalachia includes Alabama, Georgia, Mississippi, and South Carolina; Central Appalachia includes Kentucky, North Carolina, Tennessee, Virginia, and West Virginia; Northern Appalachia includes Maryland, New York, Ohio, and Pennsylvania; US non-Appalachia includes all counties not in Appalachia.

  • cThe rate ratio indicates that the rate is significantly different than the US non-Appalachia rate (P < 0.05).