Effects of exercise interventions on IGF1 and IGF2
| Within group analysis | Between groups analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| Author, year | Baseline [1] [Mean (SD)] | 1st endpoint [2] [Mean (SD)] | 2nd endpoint [3] [Mean (SD)] | Mean change [Mean (SD)] | Δ percentage | P value | P value | |
| IGF1 (ng.mL−1) | ||||||||
| 1 | Fairey et al., | I: 67.4 (29.1) | 62.5 (23.9) | NA | −4.9 (10.7) | −7.3% | NA | P = 0.045 |
| 2003 (29) | C: 70.0 (21.5) | 72.6 (24.8) | NA | 2.5 (14.8) | 3.6% | NA | ||
| 2 | Schmitz et al., | I: 172.9 (11.6) | 181.2 (11.6) | NA | 8.3 (6.3) | 4.8% | NA | P = 0.16 |
| 2005 (35)a | C: 194.3 (11.4) | 190.3 (11.4) | NA | −4.0 (6.1) | −2.0% | NA | ||
| 3 | Irwin et al., | I: 213.3 (12.6) | 207.1 (11.2) | NA | −7.4 (6.0) | −2.9% | NA | P = 0.026 |
| 2009 (31)b | C: 232.3 (18.7) | 243.7 (18.5) | NA | 12.7 (6.4) | 4.8% | NA | ||
| 4 | Galvao et al., | I: 158.9 (19.4) | 161.4 (16.1) | 156.3 (14.3) | NA | (1–2) 1.6% | P > 0.05 | NA |
| 2008 (30)b | (1–3) −1.6% | |||||||
| (2–3) −3.2% | ||||||||
| 5 | Janelsins et al., | I: 156.8 (19.6) | 129.5 (43.8) | NA | −27.3 (45.1) | −17.4% | NA | P > 0.05 |
| 2011 (32) | C: 111.8 (82.6) | 95.1 (58.7) | NA | −16.6 (66.5) | −14.9% | NA | ||
| 6 | Lee et al., 2013 (33) | I: 135.4 (60.2) | 159.5 (62.1) | NA | NA | 17.8% | P = 0.007 | NA |
| 7 | Santa Mina | I (A): 159.6 (55.2) | 169.7 (67.5) | 161.9 (45.9) | NA | (1–2) 6.3% | NA | (1–2) P = 0.129 |
| et al., 2013 (34) | (1–3) 1.4% | (1–3) P = 0.199 | ||||||
| (2–3) −4.6% | ||||||||
| I (R): 159.1 (51.2) | 138.3 (42.6) | 146.4 (49.5) | NA | (1–2) −13.1% | (1–2) P ≤ 0.05 | NA | ||
| (1–3) −8.0% | ||||||||
| (2–3) 5.9% | ||||||||
| IGF2 (ng.mL−1) | ||||||||
| 1 | Fairey et al., | I: 824.9 (155.5) | 805.0 (139.9) | NA | −19.9 (97.1) | −2.4% | NA | P = 0.101 |
| 2003 (29) | C: 714.5 (148.9) | 735.3 (152.4) | NA | 20.9 (80.5) | 2.9% | NA | ||
| 2 | Schmitz et al., | I: 898.0 (34.9) | 871.8 (34.9) | NA | −26.2 (16.7) | −3.0% | NA | P = 0.02 |
| 2005 (35)a | C: 891.3 (34.4) | 919.5 (34.4) | NA | 28.3 (16.3) | 3.2% | NA | ||