Table 3.

Characteristics of invasive breast tumors (stage, lymph node involvement, tumor size, ER, PR, and HER2 status), by periodontal disease status, WHI OS

Periodontal disease
TotalYesNo
(n = 2,124)(n = 616)(n = 1,508)Pa
Stage
 Localized1,590454 (75.3)1,136 (76.7)0.51
 Regional or distant495149 (24.7)346 (23.3)
 Missing391326
Nodal status
 Negative1,445418 (75.2)1,027 (76.5)0.53
 Positive453138 (24.8)315 (23.5)
 Missing22660166
Tumor size
 <2 cm1,431414 (71.6)1,017 (71.8)0.54
 2–4.9 cm498141 (24.4)357 (25.2)
 ≥5 cm6623 (4.0)43 (3.0)
 Missing1293891
ER/PR status
 ER+PR+1,391405 (70.9)986 (69.7)0.67
 ER+PR−29087 (15.2)203 (14.3)
 ER−PR+174 (0.7)13 (0.9)
 ER−PR−28875 (13.1)213 (15.1)
 Missing1384593
ER status
 Positive1,704496 (86.0)1,208 (84.1)0.28
 Negative31081 (14.0)229 (15.9)
 Missing1103971
PR status
 Positive1,408409 (71.4)999 (70.6)0.71
 Negative581164 (28.6)417 (29.4)
 Missing1354392
HER2 status
 Positive26574 (13.8)191 (14.6)0.64
 Negative1,579463 (86.2)1,116 (85.4)
 Missing28079201
  • aP value, χ2 test.