Table 2.

HRs with 95% CIs for different BMI and smoking categories resulting from the fully adjusted model (statistically significant values are indicated in bold)

BMIaSmokingb (cigarette equivalents per day)
Cancer siteDeaths (n)≥25–< 30≥30FormerLight (<20)Heavy (≥20)
All sites2,3791.01 (0.92–1.10)1.15 (1.01–1.32)1.31 (1.16–1.47)1.37 (1.22–1.53)2.32 (2.04–2.63)
Lung4260.95 (0.77–1.17)0.80 (0.57–1.14)2.29 (1.643.20)3.11 (2.264.26)9.86 (7.2913.33)
Colon or rectum2501.11 (0.84–1.46)1.30 (0.87–1.95)1.13 (0.80–1.58)0.99 (0.69–1.42)0.87 (0.53–1.45)
UADTc1250.71 (0.48–1.05)0.78 (0.42–1.43)1.84 (1.033.29)2.62 (1.534.49)5.45 (3.189.34)
Blood2461.02 (0.77–1.35)1.13 (0.74–1.74)1.14 (0.80–1.62)1.00 (0.70–1.43)1.16 (0.74–1.81)
Pancreas1271.20 (0.81–1.78)1.60 (0.93–2.75)1.46 (0.89–2.40)1.46 (0.89–2.39)1.84 (1.013.37)
Bladder850.62 (0.38–1.02)1.16 (0.62–2.18)1.01 (0.53–1.95)1.22 (0.65–2.29)2.57 (1.334.93)
Liver811.28 (0.77–2.12)2.21 (1.184.15)2.14 (1.144.01)1.76 (0.91–3.42)3.41 (1.746.70)
Stomach741.19 (0.72–1.98)1.45 (0.71–2.95)1.23 (0.66–2.27)0.60 (0.27–1.34)1.34 (0.62–2.91)
Female breast2011.16 (0.84–1.60)1.07 (0.64–1.79)0.79 (0.49–1.29)0.77 (0.49–1.21)1.38 (0.82–2.33)
Female genitalsd1321.31 (0.88–1.95)1.88 (1.103.20)1.21 (0.69–2.12)1.48 (0.92–2.36)1.16 (0.52–2.58)
Prostate1701.45 (1.032.04)1.54 (0.93–2.55)1.12 (0.76–1.66)1.38 (0.93–2.05)0.68 (0.35–1.29)
Remaining4620.89 (0.73–1.09)1.08 (0.80–1.46)1.22 (0.94–1.58)1.18 (0.91–1.54)1.53 (1.122.09)

NOTE: Models are adjusted for sex (where appropriate), age, survey, alcohol consumption, frequency of PA, civil status, years of education, nationality, and healthy diet.

Sex-specific results can be found in Supplementary Table S3.

  • aReference: BMI < 25 kg/m2.

  • bReference: never smoking. One pipe or cigarillo correspondent to two and one cigar to four cigarette equivalents.

  • cCancer of UADT: malignant growth of lips, oropharynx, nasopharynx, piriform sinus, laryngopharynx, oesophagus, and larynx.

  • dCancer of female genitals: malignant growth of vulva, vagina, cervix uteri, corpus uteri, ovary, and placenta.