Table 4.

Use of cobas-like partial HPV typing in triage of ASC-US

HPV-type positiveHPV-type negative
3-Year risk of CIN3+95% CI3-Year risk of CIN3+95% CI
HPV1614.5%13.5%–15.5%3.5%3.3%–3.6%
HPV184.8%4.1%–5.7%3.3%3.2%–3.5%
HPV HR3.5%3.3%–3.6%2.8%2.5%–3.2%

NOTE: The estimated CIN3+ risk among all women with ASC-US testing HC2+, prior to typing, was 5.2%; by current U.S. guidelines all would be referred to colposcopy. Three-year cumulative risk of CIN3 or worse (CIN3+) among women with Hybrid Capture 2–positive (HC2+) ASC-US, ages 21 years and older, stratified by HPV type status [HPV16, else HPV18, else other 12 high-risk (HR) types targeted by cobas].