Table 2.

Numbera and rateb of gallbladder cancer incident casesc by tumor characteristics, United States, 2007–2011

N (%)Rate95% CI
Summary stage
 Local395 (11%)0.12(0.12–0.13)
 Regional extension only1,032 (30%)0.33(0.32–0.34)
 Regional extension and/or regional lymph nodes involved444 (13%)0.14(0.13–0.14)
 Distant extension or distant lymph nodes involved1,473 (42%)0.46(0.45–0.47)
 Unknown144 (4%)0.05(0.04–0.05)
Grade
 Well (I)332 (9%)0.10(0.10–0.11)
 Moderate (II)1,007 (28%)0.31(0.3–0.32)
 Poorly (III)1,044 (29%)0.32(0.31–0.33)
 Undifferentiated (IV)69 (2%)0.02(0.02–0.02)
 Unknown1,099 (31%)0.34(0.33–0.35)
Histology
 Squamous cell carcinoma 8070–807848 (1%)0.02(0.01–0.02)
 Adenocarcinoma 8140–85763,138 (88%)0.97(0.95–0.98)
  Adenocarcinoma NOS 8140, 8141, 8143, 81472,412 (68%)0.74(0.73–0.76)
  Adenocarcinoma intestinal type 814419 (1%)0.01(0.01–0.01)
  Papillary adenocarcinoma 8260–8263129 (4%)0.04(0.04–0.04)
  Mucinous adenocarcinoma 8480–8481109 (3%)0.03(0.03–0.04)
  Signet ring cell carcinoma 849070 (2%)0.02(0.02–0.02)
  Adenosquamous carcinoma 8560, 856283 (2%)0.03(0.02–0.03)
  Endocrine tumors 8150–8157, 8240–8249, 857463 (2%)0.02(0.02–0.02)
  Other adenocarcinoma254 (7%)0.08(0.07–0.08)
 All others365 (10%)0.11(0.11–0.12)
  Neoplasm unspecified 8000–800585 (2%)0.03(0.02–0.03)
  Carcinoma NOS 8010–8015196 (6%)0.06(0.06–0.06)
  Carcinoma undifferentiated NOS 8020–802210 (0%)0.00(0–0)
  Small cell 8041–804326 (1%)0.01(0.01–0.01)
  Papillary carcinoma 8050–8052<16 (0%)0.00(0–0)
  Carcinosarcoma 8980–8982<16 (0%)0.00(0–0)
  Remaining values30 (1%)0.01(0.01–0.01)
  • aAverage annual number of cases.

  • bPer 100,000 persons, age-adjusted to the 2000 U.S. standard population.

  • cAll analyses exclude cases identified only by death certificate or autopsy. Analysis by stage further excludes cases from Minnesota.