Table 1.

Characteristics of controls and cases with colorectal cancer, stratified by sex

WomenMen
ControlsCRCControlsCRC
Variablen = 5,747n = 5,644Pan = 4,539n = 4,582Pa
Smoking status<0.001<0.001
 Never3,029 (52.9)2,819 (50.2)1,706 (37.9)1,525 (33.6)
 Former2,145 (37.4)2,126 (37.9)2,365 (52.6)2,422 (53.3)
 Current554 (9.7)669 (11.9)428 (9.5)594 (13.1)
 Missing19304041
BMI (kg/m2)<0.001<0.001
 <252,699 (47.0)2,347 (41.6)1,637 (36.1)1,324 (28.9)
 25–29.991,935 (33.7)1,964 (34.8)2,223 (49.0)2,344 (51.2)
 ≥301,113 (19.4)1,333 (23.6)679 (15.0)914 (19.9)
Family history<0.001<0.001
 No4,806 (86.0)4,483 (82.0)3,685 (89.9)3,430 (82.1)
 Yes782 (14.0)986 (18.0)414 (10.1)749 (17.9)
 Missing159175440403
Diabetes<0.0010.01
 No4,742 (95.0)4,362 (91.1)3,262 (91.0)3,289 (89.2)
 Yes249 (5.0)428 (8.9)323 (9.0)400 (10.8)
 Missing756854954893
Aspirin/NSAID use<0.001<0.001
 No3,553 (62.0)3,895 (69.3)2,519 (55.7)2,928 (64.3)
 Yes2,176 (38.0)1,727 (30.7)2,004 (44.3)1,626 (35.7)
 Missing18221628
Fruit (servings/day)<0.0010.01
 Q11,052 (19.1)1,072 (20.3)780 (18.0)824 (19.6)
 Q22,101 (38.2)2,226 (42.1)1,905 (43.9)1,917 (45.7)
 Q31,397 (25.4)1,204 (22.7)982 (22.6)888 (21.2)
 Q4952 (17.3)790 (14.9)673 (15.5)566 (13.5)
 Missing245352199387
Vegetables (servings/day)<0.001<0.001
 Q11,222 (22.2)1,328 (24.9)805 (18.5)863 (20.5)
 Q21,825 (33.1)1,824 (34.3)1,791 (41.1)1,832 (43.5)
 Q31,394 (25.3)1,209 (22.7)1,086 (24.9)893 (21.2)
 Q41,071 (19.4)962 (18.1)673 (15.5)623 (14.8)
 Missing235321184371
Processed meat (servings/day)<0.001<0.001
 Q1893 (19.1)787 (19.0)837 (23.4)634 (18.6)
 Q21,914 (41.0)1,514 (36.4)1,413 (39.5)1,281 (37.6)
 Q31,117 (23.9)1,108 (26.7)698 (19.5)780 (22.9)
 Q4742 (15.9)745 (17.9)630 (17.6)714 (20.9)
 Missing1,0811,4909611,173
Red meat (servings/day)0.001<0.001
 Q11,489 (26.8)1,235 (23.7)1,228 (28.2)949 (22.9)
 Q21,439 (25.9)1,378 (26.4)1,325 (30.4)1,177 (28.4)
 Q31,421 (25.6)1,371 (26.3)1,009 (23.1)1,077 (26.0)
 Q41,207 (21.7)1,232 (23.6)798 (18.3)940 (22.7)
 Missing191428179439
Menopause hormone therapy<0.001
 No3,062 (58.9)3,334 (67.6)
 Yes2,139 (41.1)1,599 (32.4)
 Missing546711

Abbreviation: CRC, colorectal cancer.

  • aP-value from χ2 tests for categorical variables. Missing categories were excluded from comparison tests.