Table 2.

Change in characteristics of patients with oropharyngeal cancer from KPNC between 1995 and 2010

	Calendar year of cancer diagnosis
Characteristic	1995	1998	2001	2004	2007	2010	P-trend^a
A. HPV-related sites^b
Total cases	52	55	71	114	96	126
Mean age, years	62.8	59.4	60.8	60.6	60.0	60.9	0.40
Male sex, %	65.4	67.3	69.0	83.3	81.3	80.2	<0.001
White race, %	90.4	70.9	91.6	86.8	82.3	84.1	0.88
Prior smoking, %					55.2	45.2	0.046
Prior alcohol abuse, %					22.9	24.6	0.98
Lower education census-tract, %	17.5	24.5	13.0	15.0	24.0	18.2	0.82
Lower income census-tract, %	2.5	5.7	4.4	2.8	4.2	3.3	0.97
B. HPV-unrelated sites^b
Total cases	77	82	91	82	95	95
Mean age, years	65.0	63.4	66.1	65.0	65.0	62.2	0.71
Male sex, %	55.8	57.3	53.9	61.0	52.6	50.5	0.23
White race, %	81.8	84.2	82.4	78.1	77.9	72.6	0.033
Prior smoking, %					61.1	48.4	0.070
Prior alcohol abuse, %					30.5	20.0	0.10
Lower education census-tract^c, %	17.4	26.3	18.8	14.6	14.7	16.5	0.15
Lower income census-tract^d, %	8.7	9.2	3.5	8.5	4.2	2.2	0.13

NOTE: Findings in bold are statistically significant.
↵^aP-trend based on linear regression for age and logistic regression for remaining variables, with calendar year as the predictor.
↵^bDefined by histologic site of cancer as described by Chaturvedi et al. (17).
↵^cLower education census-tract defined as ≥25% population with less than a high school education.
↵^dLower income census-tract defined as ≥20% population with household income below poverty levels.