Table 2.

Gene-level significant occupational exposure interactions for established/suspected occupational lung carcinogens

CHRGENENumber of SNPsStart BPEnd BPORP
Metals
 Chromate and compounds1C1orf10126242691315242870285121.680.000052
 Chlorinated solvents1HRNR715045118115046329356.060.000078
Organic dust
 Animal feeding19ELAVL11479294567976529108.840.000009
Silica
 Brick dust16AQP811251357852514775464.700.000056
7CPA425129720229129751250155.950.000086
7CPA527129771865129795807178.970.000042
 Cement dust4ANKRD5615780351057803802683.150.000018
1CD4612205992024206035481119.340.000095
12DAZAP210499188924992383489.700.000038
12LOC5722812499253994995046995.210.000055
22RTN4R21186089371863581686.810.000096
 Concrete dust17ARSG336376691763928595125.100.000053
 Respirable-free crystalline silica5MGC421058432280834331670965.890.000027
 Sand2COL5A21418960488518975285089.210.000051
3LBA1183684331436877415116.150.000023

Abbreviations: BP, base-pair; CHR, chromosome.