Table 4.

Multivariate-adjusted OR and 95% CI of colorectal adenoma according to NAT2 acetylation genotype

MenWomen
NAT2 acetylation genotypeCase/controlsOR (95% CI)aCase/controlsOR (95% CI)a
Slow40/341.00 (ref.)19/141.00 (ref.)
Intermediate187/1691.00 (0.59–1.68)90/990.64 (0.29–1.41)
Rapid220/2070.91 (0.54–1.52)108/1030.69 (0.32–1.52)
Ptrend0.540.69
Rapid vs. slow/intermediate0.91 (0.69–1.20)1.01 (0.68–1.51)
  • aAdjusted for age, screening period, smoking, alcohol consumption, body mass index, physical activity, family history of colorectal cancer, and NSAID use. Further adjusted for age at menarche, menopausal status, and current use of hormones in women.