Table 2.

Race/ethnicity-specific associations between history of comorbidities and overall mortality and breast cancer–specific mortality, CBCSC, diagnoses 1993–2007

Previous cancerDiabetesHBP or hypertensionMyocardial infarction
OverallBC-specificOverallBC-specificOverallBC-specificOverallBC-specific
HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)
All patientsa1.30 (1.12–1.50)1.11 (0.87–1.40)1.75 (1.50–2.05)1.48 (1.18–1.87)1.15 (1.05–1.27)0.91 (0.79–1.06)1.45 (1.15–1.92)1.94 (1.27–2.97)
Non–Latina whitesb1.18 (0.99–1.41)1.09 (0.81–1.47)1.94 (1.52–2.47)1.63 (1.10–2.43)1.26 (1.12–1.42)0.93 (0.76–1.14)1.44 (1.06–1.95)1.82 (1.04–3.16)
African Americansb1.36 (0.85–2.17)0.91 (0.48–1.71)1.54 (1.06–2.22)1.17 (0.72–1.90)1.15 (0.88–1.51)1.07 (0.78–1.47)1.97 (0.99–3.93)1.71 (0.70–4.13)
Latinasb2.56 (1.36–4.77)3.20 (1.37–7.46)3.04 (1.92–4.81)1.50 (0.71–3.17)1.02 (0.70–1.48)0.73 (0.41–1.28)0.30 (0.01–28.6)Not available
Asian Americansb2.16 (1.23–3.86)1.85 (0.77–4.46)1.92 (1.31–2.84)1.43 (0.84–2.44)0.88 (0.64–1.20)c0.52 (0.33–0.81)d2.01 (0.69–5.82)1.10 (0.15–8.33)

Abbreviation: BC, breast cancer.

  • aAdjusted for race/ethnicity, age, stage (AJCC), hormone receptor status, nodal involvement, grade, tumor size, surgery type, chemotherapy, radiotherapy, prior cancer, BMI, education, neighborhood SES, nativity, marital status, menopausal status, age at first birth, smoking, and alcohol consumption.

  • bAs above, but no adjustment for race/ethnicity.

  • cPinteraction of non–Latina white versus Asian American with hypertension for overall mortality = 0.03.

  • dPinteraction of non–Latina white versus Asian American with hypertension for breast cancer–specific mortality = 0.01.