Table 1.

Characteristics of patients with breast cancer with a history of comorbiditiesa, CBCSC, diagnoses 1993–2007

Previous cancerDiabetesHBP or hypertensionMyocardial infarction
TotalYes (%)TotalYes (%)TotalYes (%)TotalYes (%)
8,952605 (6.8)8,946489 (5.5)8,9522,479 (27.7)8,108136 (1.7)
Age, y
 <40511 (5.7)13 (2.1)511 (5.7)15 (3.1)511 (5.7)32 (1.3)456 (5.6)0 (0)
 40–491,752 (19.6)72 (11.9)1,751 (19.6)72 (14.7)1,752 (19.6)273 (11.0)1,491 (18.4)13 (9.6)
 50–592,662 (29.7)147 (24.3)2,659 (29.7)125 (25.6)2,662 (29.7)682 (27.5)2,435 (30.0)23 (16.9)
 60–692,229 (24.9)163 (26.9)2,229 (24.9)163 (33.3)2,229 (24.9)751 (30.3)2,054 (25.3)34 (25.0)
 ≥701,798 (20.1)210 (34.7)1,796 (20.1)114 (23.3)1,798 (20.1)741 (29.9)1,672 (20.6)66 (48.5)
P<0.0001<0.0001<0.0001<0.0001
Race/ethnicity
 Non–Latina white5,683 (63.5)455 (75.2)5,682 (63.5)171 (35.0)5,683 (63.5)1,391 (56.1)5,550 (68.5)96 (70.6)
 African American882 (9.9)51 (8.4)880 (9.8)101 (20.7)882 (9.9)399 (16.1)776 (9.6)21 (15.4)
 Latina928 (10.4)46 (7.6)925 (10.3)104 (21.3)928 (10.4)270 (10.9)324 (4.0)5 (3.7)
 Asian American1,354 (15.1)48 (7.9)1,354 (15.1)109 (22.3)1,354 (15.1)392 (15.8)1,354 (16.7)12 (8.8)
 Other105 (1.2)5 (0.8)105 (1.2)4 (0.8)105 (1.2)27 (1.1)104 (1.3)2 (1.5)
P<0.0001<0.0001<0.00010.02
Neighborhood SESb
 Lowest543 (6.1)34 (5.6)542 (6.1)63 (12.9)543 (6.1)206 (8.3)507 (6.3)10 (7.4)
 Lower-middle1,105 (12.3)70 (11.6)1,103 (12.3)104 (21.3)1,105 (12.3)372 (15.0)969 (12.0)17 (12.5)
 Middle1,669 (18.6)133 (22.0)1,668 (18.6)116 (23.7)1,669 (18.6)492 (19.8)1,492 (18.4)35 (25.7)
 Higher-middle2,314 (25.8)142 (23.5)2,313 (25.9)99 (20.2)2,314 (25.8)615 (24.8)2,096 (25.9)34 (25.0)
 Highest3,049 (34.1)204 (33.7)3,048 (34.1)99 (20.2)3,049 (34.1)724 (29.2)2,783 (34.3)37 (27.2)
 Unknown272 (3.0)22 (3.6)272 (3.0)8 (1.6)272 (3.0)70 (2.8)261 (3.2)3 (2.2)
P0.25<0.0001<0.00010.27
Tumor stage (AJCC)
 I4,381 (48.9)328 (54.2)4,378 (48.9)202 (41.3)4,381 (48.9)1,214 (49.0)4,013 (49.5)79 (58.1)
 II3,674 (41.0)217 (35.9)3,671 (41.0)225 (46.0)3,674 (41.0)1,029 (41.5)3,290 (40.6)45 (33.1)
 III503 (5.6)27 (4.5)503 (5.6)31 (6.3)503 (5.6)127 (5.1)443 (5.5)6 (4.4)
 IV129 (1.4)8 (1.3)129 (1.4)12 (2.5)129 (1.4)29 (1.2)117 (1.4)1 (0.7)
 Unknown265 (3.0)25 (4.1)265 (3.0)19 (3.9)265 (3.0)80 (3.2)245 (3.0)5 (3.7)
P0.0140.0240.320.56
Breast surgery
 None141 (1.6)19 (3.1)141 (1.6)13 (2.7)141 (1.6)41 (1.7)126 (1.6)2 (1.5)
 Mastectomy3,817 (42.6)241 (39.8)3,815 (42.6)230 (47)3,817 (42.6)1,108 (44.7)3,457 (42.6)71 (52.2)
 Breast-conserving surgery4,982 (55.7)345 (57.0)4,978 (55.6)246 (50.3)4,982 (55.7)1,326 (53.5)4,513 (55.7)63 (46.3)
 Other12 (0.1)0 (0)12 (0.1)0 (0)12 (0.1)4 (0.2)12 (0.1)0 (0)
P0.0060.0020.140.12
Chemotherapy
 No4,898 (54.7)392 (64.8)4,894 (54.7)284 (58.1)4,898 (54.7)1,545 (62.3)4,507 (55.6)102 (75.0)
 Yes3,910 (43.7)203 (33.6)3,908 (43.7)197 (40.3)3,910 (43.7)905 (36.5)3,470 (42.8)33 (24.3)
 Unknown144 (1.6)10 (1.7)144 (1.6)8 (1.6)144 (1.6)29 (1.2)131 (1.6)1 (0.7)
P<0.00010.38<0.0001<0.0001
Radiotherapy
 No4,187 (46.8)307 (50.7)4,185 (46.8)255 (52.1)4,187 (46.8)1,220 (49.2)3,848 (47.5)77 (56.6)
 Yes4,765 (53.2)298 (49.3)4,761 (53.2)234 (47.9)4,765 (53.2)1,259 (50.8)4,260 (52.5)59 (43.4)
P0.040.020.0130.08
BMI (kg/m2)
 <25.04,657 (52.0)336 (55.5)4,534 (50.7)120 (24.5)4,534 (50.6)844 (34.0)4,278 (52.8)57 (41.9)
 25.0 to ≤29.92,469 (27.6)150 (24.8)2,589 (28.9)133 (27.2)2,592 (29.0)832 (33.6)2,301 (28.4)41 (30.1)
 30.0 to ≤34.91,032 (11.5)67 (11.1)1,032 (11.5)135 (27.6)1,032 (11.5)473 (19.1)842 (10.4)22 (16.2)
 ≥35.0562 (6.3)32 (5.3)559 (6.2)88 (18.0)562 (6.3)268 (10.8)465 (5.7)12 (8.8)
 Unknown232 (2.6)20 (3.3)232 (2.6)13 (2.7)232 (2.6)62 (2.5)222 (2.7)4 (2.9)
P0.22<0.0001<0.0001<0.0001
  • aNo and unknown conditions are not shown for the five comorbidities.

  • bNeighborhood SES is measured using the Yost SES index, which is a composite measure of 7 Census indicator variables.