Table 2.

ICC and association between weight and methylation levels for probes with P < 10−5

Cross-sectional, T0Cross-sectional, T1Longitudinal
ProbeGeneType of probePosition (HG b37)ICCβaPβaPβaP
cg08536358PDHA2II967600140.01−0.8423.4 × 10−7−0.0140.214−0.4007.1 × 10−7
cg12641838PSMB9I328220130.02−0.1643.1 × 10−6−0.0220.252−0.0941.8 × 10−6
cg14233050PXNII1206518710.000.8265.7 × 1070.0070.2560.3832.3 × 106
cg12354986TRIOBPI381421740.25−0.0474.2 × 10−4−0.0550.001−0.0522.6 × 10−6
cg05838155FBXL20I375572760.09−0.0290.003−0.0230.005−0.0285.4 × 10−6
cg17501210RPS6KA2II1669702520.74−0.0310.002−0.0350.001−0.0398.2 × 10−6
cg1045377713q21.2II622452290.14−0.0100.129−0.0272.3 × 10−5−0.0209.5 × 10−6

NOTE: Bolded results have consistent direction of association for cross-sectional analyses in T0 and T1, and longitudinal analyses for weight change between T0 and T1.

  • aβ coefficient per 5 kg change in weight (kg).