Table 3.

SNPs that enter stepwise regression

SNPAlt Rs#ChrBPA1A2InfoβPaTypeNearest gene
Cotinine glucuronidation
 rs115765562rs34100980469673553CA1.13770.18331.60E−155IntergenicUGT2B10
 rs141360540rs10028938469669216GA0.9535−0.15875.51E−91IntergenicUGT2B10
 rs115219551rs9997650469669388AG0.8903−0.09411.70E−50IntergenicUGT2B10
 rs294777469682471AG1.22440.19055.53E−48IntronicUGT2B10
 rs6832720458148386AG1.2635−0.05857.36E−09IntergenicOC255130
 rs1115363467073143AT0.96970.09747.38E−09IntergenicLOC100144602
 rs6952407766045512AG1.17190.0334.51E−09IntergenicLOC493754/KCTD7
 rs606346379110873780TC1.04620.09422.14E−08IntergenicKLF4/ACTL7B
 rs47505351014633024CT1.09470.09992.99E−10IntronicFAM107B
 rs42873041116559630CT0.8419−0.10282.53E−09IntronicSOX6
 chr12:7996130:Drs202090541127996130ACA0.92220.0613.88E−08IntronicNECAP1/SLC2A14
 rs765133441463047683CA1.0516−0.09952.16E−09IntergenicKCNH5
 rs8033202315101073444CT1.0749−0.123.35E−08IntronicCERS3/LASS3
 rs602835481597454880CT1.062−0.13273.57E−08Intergenic7SK/SPATA8
 rs347052751943933725AC1.1580.03373.91E−08IntergenicTEX101/LYPD3
Nicotine glucuronidation
 rs116224959rs835315469685772GA1.13260.11932.56E−43IntronicUGT2B10
 rs4132568796134981AC1.0853−0.03432.69E−08IntronicSHFM1
  • aOverall P values were analyzed via linear regression in PLINK with adjustment for age, sex, race, principal components 1 to 10, and nicotine equivalents.