Table 2.

Selected potential targets of PCA3-shRNA2

Gene IDGene name8Mer7Mer-M87Mer-1AMicroarray expression: fold change <1.0 and P < 0.05Fold change [DU145 and PCA3-shRNA2 (mean ± SD)]Cell adhesionCell growthCell surface signalingGrowth regulationAntiproliferativeProtein signalingTranscriptional regulationTGFB signalingTransmembrane signalingUrogenital/sex development
COPS2COP9 subunit 211000.24 ± 0.151
SOX11SRY (sex determining region Y)-box 1110000.36 ± 0.3111
WDR48WD repeat domain 4810010.51 ± 0.2
TEAD1TEA domain family member 110110.57 ± 0.321
NOGNoggin10000.72 ± 0.27111112
WDR1WD repeat domain 110010.86 ± 0.32
INVSInversin10001.06 ± 0.5311
CDH2N-cadherin10011.37 ± 1.871
MAP3K1Mitogen-activated protein kinase kinase kinase 110001.54 ± 0.93111111
ETV5Ets variant gene 510011.55 ± 0.391
KIAA0515KIAA051520001.59 ± 1.35
ETV1Ets variant gene 110003.35 ± 3.21