Table 1.

Characteristics of women participating in the study at two points in time, T0 and T1, approximately 6 years apart

T0T1
Individuals, N9292
Age at blood collection, years, median (range)53 (35–77)59 (41–83)
Age at menarche, years, median (range)13 (10–17)N/A
Menopausal status
 Premenopausal, N (%)33 (36%)13 (14%)
 Postmenopausal (excluding current HRT users), N (%)41 (45%)61 (66%)
 Undetermined/on HRT, N (%)18 (20%)18 (20%)
Age at menopause (postmenopausal only, excluding current HRT users), years, median (range)50 (29–56)52 (40–58)
Parity
 Nulliparous, N (%)14 (15%)No change
 Parous, N (%)78 (85%)No change
Age at first birth (parous only), years, median (range)25 (18–39)No change
OC use
 Never, N (%)21 (23%)20 (22%)
 Former, N (%)70 (76%)62 (67%)
 Current, N (%)1 (1%)0 (0%)
 Missing, N (%)0 (0%)10 (11%)
HRT use (postmenopausal only)
 Never, N (%)25 (46%)37 (51%)
 Former, N (%)16 (30%)24 (33%)
 Current, N (%)13 (24%)7 (10%)
 Missing, N (%)0 (0%)4 (6%)
Weight, kg, median (range)65 (49–127)66 (49–121)
Weight change between T0 and T1, kg, median (range)1 (−16–18)
Body mass index, median (range)24 (20–51)25 (19–49)
Regular alcohol use
 No, N (%)18 (20%)7 (8%)
 Yes, N (%)74 (80%)74 (80%)
 Missing, N (%)0 (0%)11 (12%)
Duration of alcohol use, years, median (range)31 (2–44)N/A
Smoking status
 Never, N (%)61 (66%)61 (66%)
 Former, N (%)28 (30%)29 (32%)
 Current, N (%)3 (3%)2 (2%)
Time since quitting, former smokers, years, median (range)26 (4–47)31.5 (10–53)
Age when started smoking (ever smokers), years, median (range)17 (14–21)N/A
WBC subtype, percentage, median (range)
 Lymphocytes
  T cells CD8+9 (3–21)10 (3–30)
  T cells CD4+15 (2–28)16 (1–26)
  Nature killer cells4 (0–14)4 (0–11)
  B cells8 (4–13)8 (5–12)
 Monocytes10 (7–18)10 (7–16)
 Granulocytes52 (38–65)51 (38–66)

Abbreviation: N/A, not assessed.