The identification of internal control microRNAs in whole bloods
Discovery cohort | ||||||
---|---|---|---|---|---|---|
Overall cancer cases vs. controls | Breast cancer cases vs. controls | Prostate cancer cases vs. controls | ||||
(20 vs. 20) | (12 vs. 12) | (8 vs. 8) | ||||
ID | Fold change | CV | Fold change | CV | Fold change | CV |
miR134 | −1.046 | 0.034 | 1.023 | 0.034 | −1.159 | 0.034 |
miR934 | 1.025 | 0.034 | 1.035 | 0.037 | 1.009 | 0.027 |
miR346 | −1.028 | 0.036 | −1.053 | 0.031 | 1.009 | 0.042 |
miR409.3p | −1.083 | 0.048 | −1.103 | 0.039 | −1.053 | 0.056 |
miR485.3p | −1.014 | 0.053 | −1.029 | 0.053 | 1.009 | 0.049 |
miR144 | 1 | 0.086 | 1.023 | 0.092 | −1.035 | 0.079 |
Validation cohort | ||||||
Overall cancer cases vs. controls | Breast cancer cases vs. controls | Prostate cancer cases vs. controls | ||||
(74 vs. 90) | (41 vs. 70) | (26 vs. 20) | ||||
ID | Fold change | CV | Fold change | CV | Fold change | CV |
miR346 | −1.054 | 0.068 | −1.006 | 0.069 | −1.113 | 0.066 |
miR134 | −1.149 | 0.051 | −1.036 | 0.05 | −1.276 | 0.052 |
miR934 | 1.504 | 0.047 | 1.464 | 0.046 | 1.568 | 0.052 |