Association of urinary PGE-M levels and risk of breast cancer stratified by median time interval between urine collection and cancer diagnosis among postmenopausal women with a BMI < 25
| Cancer diagnosed ≤ 4 years after sample collection | Cancer diagnosed > 4 years after sample collection | |||
|---|---|---|---|---|
| PGE-M, ng/mg Cr | Cases/controls | OR (95% CI)a | Cases/controls | OR (95% CI)a |
| Q1 (<2.10) | 10/88 | 1.00 (ref.) | 16/88 | 1.00 (ref.) |
| Q2 (2.11–2.40) | 15/87 | 1.30 (0.53–3.20) | 15/87 | 0.79 (0.35–1.82) |
| Q3 (2.41–2.68) | 21/85 | 2.55 (1.06–6.14) | 10/85 | 1.02 (0.44–2.40) |
| Q4 (>2.68) | 22/73 | 3.57 (1.51–8.43) | 16/73 | 1.30 (0.58–2.91) |
| Plinear trend | <0.001 | 0.435 | ||
↵aDerived from unconditional logistic regression and adjusted for age (continuous variable), education (<high school or ≥high school), cigarette smoking status (nonsmokers or ever-smokers), number of live births (0, 1, or ≥2), and months of breastfeeding (four levels: <6.0, 6.0–11.9, 12.0–24.0, and >24.0).