Colorectal cancer and colorectal cancer plus high-risk adenoma prevalence as a function of FL-DNA evaluation and negative iFOBT and positive iFOBT separated by the median value of all positive iFOBT detected
Colorectal cancer | ||||||
---|---|---|---|---|---|---|
RT FL-DNA | Yes N (%) | No N (%) | Likelihood ratio (95% CI) | iFOBT <100Posttest probability(pretest = 0.0128) | iFOBT 100–432Posttest probability(pretest = 0.116) | iFOBT >432Posttest probability(pretest = 0.381) |
0–9 | 6 (26.1) | 174 (79.8) | 0.327 (0.156–0.683) | 0.004 | 0.041 | 0.168 |
10–30 | 4 (17.4) | 39 (17.9) | 0.972 (0.398–2.374) | 0.012 | 0.113 | 0.374 |
≥30 | 13 (56.5) | 5 (2.3) | 24.643 (17.210–35.288) | 0.242 | 0.764 | 0.938 |
Total | 23 (100) | 218 (100) | ||||
Colorectal cancer and high-risk adenoma | ||||||
RT FL-DNA | Yes N (%) | No N (%) | Likelihood ratio (95% CI) | iFOBT <100Posttest probability(pretest = 0.160) | iFOBT 100–432Posttest probability(pretest = 0.256) | iFOBT >432Posttest probability(pretest = 0.500) |
0–9 | 34 (59.7) | 146 (79.4) | 0.752 (0.527–1.072) | 0.125 | 0.206 | 0.429 |
10–30 | 8 (14.0) | 35 (19.0) | 0.738 (0.387–1.408) | 0.123 | 0.203 | 0.425 |
≥30 | 15 (26.3) | 3 (1.6) | 16.140 (10.449–24.931) | 0.755 | 0.847 | 0.942 |
Total | 57 (100) | 184 (100) |