Table 5.

Colorectal cancer and colorectal cancer plus high-risk adenoma prevalence as a function of FL-DNA evaluation and negative iFOBT and positive iFOBT separated by the median value of all positive iFOBT detected

Colorectal cancer
RT FL-DNAYes N (%)No N (%)Likelihood ratio (95% CI)iFOBT <100Posttest probability(pretest = 0.0128)iFOBT 100–432Posttest probability(pretest = 0.116)iFOBT >432Posttest probability(pretest = 0.381)
0–96 (26.1)174 (79.8)0.327 (0.156–0.683)0.0040.0410.168
10–304 (17.4)39 (17.9)0.972 (0.398–2.374)0.0120.1130.374
≥3013 (56.5)5 (2.3)24.643 (17.210–35.288)0.2420.7640.938
Total23 (100)218 (100)
Colorectal cancer and high-risk adenoma
RT FL-DNAYes N (%)No N (%)Likelihood ratio (95% CI)iFOBT <100Posttest probability(pretest = 0.160)iFOBT 100–432Posttest probability(pretest = 0.256)iFOBT >432Posttest probability(pretest = 0.500)
0–934 (59.7)146 (79.4)0.752 (0.527–1.072)0.1250.2060.429
10–308 (14.0)35 (19.0)0.738 (0.387–1.408)0.1230.2030.425
≥3015 (26.3)3 (1.6)16.140 (10.449–24.931)0.7550.8470.942
Total57 (100)184 (100)