Table 1.

Baseline characteristics by case status

Cases (n = 998)
Baseline characteristicsControls (n = 999)TotalPAggressiveaPNonaggressivebP
AMH quartiles (ng/mL)0.5990.2830.525
 Q1 (0.04–2.64)248 (24.8%)222 (22.2%)78 (21.3%)134 (22.0%)
 Q2 (2.65–4.21)249 (24.9%)260 (26.1%)107 (29.2%)150 (24.6%)
 Q3 (4.22–6.74)252 (25.2%)260 (26.1%)97 (26.4%)159 (26.1%)
 Q4 (6.75–25.0)250 (25.0%)256 (25.7%)85 (23.2%)167 (27.4%)
Age at randomization, y1.0000.1800.462
 ≤59151 (15.1%)151 (15.1%)40 (10.9%)109 (17.9%)
 60–64345 (34.5%)346 (34.7%)127 (34.6%)211 (34.6%)
 65–69327 (32.7%)325 (32.6%)124 (33.8%)193 (31.6%)
 ≥70176 (17.6%)176 (17.6%)76 (20.7%)97 (15.9%)
Marital status0.0980.5620.052
 Married or living as married861 (86.2%)882 (88.4%)319 (86.9%)545 (89.3%)
 Singlec138 (13.8%)113 (11.3%)46 (12.5%)64 (10.5%)
First-degree relative(s) with prostate cancer<0.001<0.001<0.001
 No924 (92.5%)864 (86.6%)320 (87.2%)524 (85.9%)
 Yes52 (5.2%)114 (11.4%)39 (10.6%)74 (12.1%)
BMI at baseline (kg/m2)0.4110.5380.399
 <25275 (27.5%)265 (26.6%)104 (28.3%)152 (24.9%)
 25–30505 (50.6%)530 (53.1%)192 (52.3%)327 (53.6%)
 ≥30210 (21.0%)190 (19.0%)67 (18.3%)122 (20.0%)
History of diabetes0.0150.0860.054
 No909 (91.0%)937 (93.9%)345 (94.0%)571 (93.6%)
 Yes85 (8.5%)57 (5.7%)21 (5.7%)36 (5.9%)
Cigarette smoking status0.0050.0010.124
 Never394 (39.4%)453 (45.4%)181 (49.3%)265 (43.4%)
 Current96 (9.6%)66 (6.6%)21 (5.7%)44 (7.2%)
 Former509 (51.0%)478 (47.9%)164 (44.7%)301 (49.3%)
Food energy from diet (kcal/d)0.4290.6040.487
 Q1 (≤1707)243 (24.3%)217 (21.7%)76 (20.7%)135 (22.1%)
 Q2 (1718–2212)244 (24.4%)268 (26.9%)97 (26.4%)168 (27.5%)
 Q3 (2213–2804)243 (24.3%)235 (23.5%)89 (24.3%)142 (23.3%)
 Q4 (≥2805)244 (24.4%)249 (24.9%)88 (24.0%)153 (25.1%)
Enlarged prostate0.0440.6770.020
 No738 (73.9%)696 (69.7%)267 (72.8%)417 (68.4%)
 Yes261 (26.1%)301 (30.2%)100 (27.2%)192 (31.5%)
Biopsy of prostate<0.0010.008<0.001
 No922 (92.3%)864 (86.6%)318 (86.6%)529 (86.7%)
 Yes56 (5.6%)105 (10.5%)35 (9.5%)67 (11.0%)

NOTE: Column percentages may not sum to 100% due to missings. P values were estimated by χ2 tests using nonmissing values. There were 21 prostate cancer cases that could not be classified to a subtype due to missing tumor characteristics.

  • aAggressive prostate cancer: biopsy Gleason ≥ 7, or clinical stage ≥III, or fatal.

  • bNonaggressive prostate cancer: biopsy Gleason ≤ 6, and clinical stage I or II.

  • cSingle: widowed/divorced/separated/never married.