Table 1.

Race-specific distributions of ER, PR, and HER2 status by age at diagnosis and grade; calculated among histologically confirmed female breast cancer cases in South Africa (2009–11, public sector) and Namibia (2011–13), restricted to women with known receptor status (n = 10,047 for ER, 8620 for PR, 8251 for HER2)

BlackWhiteMixed ancestryIndian/AsianOther/unknown
ERN = 5,559% ER (33.8)N = 1,963% ER (26.0)N = 1,556% ER (31.1)N = 313% ER (28.4)N = 656% ER (36.4)
Age at diagnosis
 20–2911627.61838.92748.2250.01250.0
 30–3975634.315525.813738.02825.08433.3
 40–491,36433.335028.636833.25932.216141.6
 50–591,37238.547634.539934.89227.215141.1
 60–691,01531.651323.235427.77230.611434.2
 ≥7093630.245117.727122.16025.013427.6
Grade
 147517.92109.118113.82711.14420.5
 22,02528.058120.744025.28822.723331.3
 31,26551.236047.526758.44254.814054.3
 NK1,79432.381224.666828.715627.623933.9
PRa,bN = 5,131% PR (47.7)N = 1,465% PR (39.0)N = 969% PR (43.6)N = 263% PR (36.1)N = 576% PR (52.3)
Age at diagnosis
 20–2910441.41855.62369.6250.01154.6
 30–3970246.712737.89952.52231.87454.1
 40–491,27144.127539.626441.75246.214955.0
 50–591,26255.436648.627151.78333.713857.3
 60–6994547.939939.122941.55635.710353.4
 ≥7088944.434534.517141.55334.011741.9
Gradeb
 145637.516627.112628.62222.73941.0
 21,94041.750834.833943.77533.322347.1
 31,21663.731160.121062.93860.513671.3
 NK1,56146.554538.738244.013333.819447.9
HER2aN = 4,686% HER2+ (24.9)N = 1,569% HER2+ (25.3)N = 1,249% HER2+ (27.6)N = 244% HER2+ (20.5)N = 503% HER2+ (24.3)
Age at diagnosis
 20–299724.71442.932119.120.01010.0
 30–3963630.712825.010930.32334.86640.9
 40–491,14027.328131.028726.54522.213126.0
 50–591,17626.537525.934329.57114.111625.9
 60–6985121.741223.527124.75819.038612.8
 ≥7078618.135921.721829.44524.49421.3
Grade
 141320.817617.114619.12512.03622.2
 21,78524.551124.338625.97617.119327.5
 3116426.033529.923633.93727.011421.9
 NK1,32425.854726.148128.510622.616023.1
  • aPR and HER2 are included only if ER is known.

  • bData from one laboratory (women of all ages) were excluded from total statistics for PR, due to age-related missing PR status. That laboratory included age-specific numbers; hence, the total number is less than the sum of the age-specific numbers.