Table 6.

Associations of prostate cancer dietary index score with prostate cancer risk

Prostate Cancer Dietary Index score
0 to 123Dose response (per 1 unit score)Ptrendd
Controls, n8,4363,120447
Overall cases, n1,31143758
 Model 1a10.90 (0.80–1.01)0.82 (0.62–1.08)
 Model 210.90 (0.80–1.02)0.82 (0.61–1.09)0.91 (0.84–0.99)0.04
Localized casesb, n1,16539849
 Model 110.92 (0.82–1.04)0.78 (0.58–1.06)
 Model 210.92 (0.81–1.04)0.78 (0.57–1.06)0.93 (0.85–1.01)0.10
Locally advanced casesb, n138379
 Model 110.71 (0.49–1.02)1.18 (0.60–2.34)
 Model 210.71 (0.49–1.04)1.17 (0.58–2.36)0.79 (0.61–1.03)0.08
Locally advanced vs. localizedc, n138/1,16537/3989/49
 Model 110.81 (0.54–1.19)1.45 (0.68–3.06)
 Model 210.84 (0.56–1.25)1.48 (0.68–3.19)0.90 (0.69–1.19)0.46
Low-grade casesb, n87329239
 Model 110.90 (0.79–1.04)0.84 (0.60–1.17)
 Model 210.89 (0.77–1.03)0.82 (0.59–1.16)0.93 (0.84–1.03)0.15
High-grade casesb, n43314419
 Model 110.89 (0.73–1.08)0.80 (0.50–1.28)
 Model 210.92 (0.75–1.12)0.83 (0.51–1.34)0.90 (0.78–1.04)0.16
High vs. low gradec, n433/873144/29219/39
 Model 110.99 (0.78–1.25)1.06 (0.60–1.88)
 Model 211.04 (0.81–1.33)1.13 (0.63–2.03)0.98 (0.82–1.18)0.86

NOTE: Model 1 for cancer subtypes: adjusted for age (continuous variable) and recruitment center; and Model 2: further adjusted for family history of prostate cancer, smoking status, and total energy intake (continuous variable).

  • aORs and 95% CIs from conditional logistic regression, matched by 5-year age band and recruitment center, and adjusted by age (continuous variable).

  • bRRRs and 95% CIs from multinomial logistic regression.

  • cRRRs and 95% CIs from logistic regression.

  • dPtrend for the association of prostate cancer risk per 1 unit increment in index score.