Table 3.

Effect of WHtR on risk of obesity-related cancers in men and women

WHtR<0.51 (m), <0.57 (f)≥0.51 (m), ≥0.57 (f)
All subjects
 Number1,4922,271
 Cancer cases/person-yearsa124/25,523261/38,779
 IR/10,000 person-years48.667.3
 HR (95% CI)
  Unadjusted1.0 (reference)1.4 (1.1–1.7)
  Adjustedb1.0 (reference)1.6 (1.3–2.0)
Males
 Cancer cases/person-yearsa20/8,01785/17,751
 IR/10,000 person-years24.947.9
 HR (95% CI)
  Unadjusted1.0 (reference)1.9 (1.2–3.1)
  Adjustedb1.0 (reference)2.0 (1.2–3.3)
Females
 Cancer cases/person-yearsa104/17,506176/21,027
 IR/10,000 person-years59.483.7
 HR (95% CI)
  Unadjusted1.0 (reference)1.4 (1.1–1.8)
  Adjustedb1.0 (reference)1.5 (1.2–2.0)

Abbreviation: IR, incidence rate.

  • aFollow-up time begins 4 years after end of exposure period.

  • bAdjusted for age, sex (in all-subjects models), height, education level, alcohol, cigarettes/day, and physical activity.