Table 4.

HRs for hormone receptor–defined invasive breast cancer according to level of recreational physical activity within the previous 4 years

ER+/PR+ER+/PRER/PR+ER/PR
Recreational physical activity (MET-h/wk)No. of casesMultivariable HRa95% CINo. of casesMultivariable HRa95% CINo. of casesMultivariable HRa95% CINo. of casesMultivariable HRa95% CI
 <122381.00(reference)941.00(reference)161.00(reference)611.00(reference)
 ≥127210.900.78–1.052840.870.69–1.10330.620.34–1.132051.000.75–1.33
Phomogeneity0.57
ER+ERPR+PR
Recreational physical activity (MET-h/wk)No. of casesMultivariable HRa95% CINo. of casesMultivariable HRa95% CINo. of casesMultivariable HRa95% CINo. of casesMultivariable HRa95% CI
 <123321.00(reference)771.00(reference)2541.00(reference)1551.00(reference)
 ≥121,0050.890.79–1.012380.920.71–1.197540.880.77–1.024890.920.77–1.10
Phomogeneity0.870.74

NOTE: Forty-one breast cancer cases occurred among women with missing information on level of recreational physical activity within the previous 4 years. E3N Cohort, 1993–2005 (n = 58,846).

  • aAdjusted for age (time scale), family history of breast cancer in first-degree relatives, age at menarche, parity and age at first full-term pregnancy, BMI, history of benign breast disease, age at menopause, use of menopausal hormone therapy, total energy intake excluding alcohol, and alcohol intake. Further stratified by year of birth. See Table 1 for the categories/cutoffs used.