Table 3.

Individual and combined biomarker performance data for bladder cancer detection

BiomarkerArea under the curve95% CINo. of correctly predicted eventsNo. of correctly predicted noneventsNo. of nonevents predicted as eventsNo. of events predicted as noneventsSensitivity (%)Specificity (%)PPV (%)NPV (%)
IL80.79020.7315–0.848874100332277.175.269.282.0
MMP90.74320.6781–0.80837981521782.360.960.382.7
SERPINA10.78700.728–0.84597096372672.972.265.478.7
ANG0.77680.7173–0.83648569641188.551.957.086.2
VEGFA0.79470.7356–0.85398986511684.862.863.684.3
CA90.80500.7488–0.861266107263068.880.571.778.1
MMP100.78680.7284–084517886471881.364.762.482.7
APOE0.75490.6933–0.81648272611485.454.157.383.7
SERPINE10.78180.7230–0.84077986471782.364.762.783.5
SDC10.80240.7451–0.85987599342178.174.468.882.5
All 10 biomarkers0.84750.7958–0.899276105282079.278.973.184.0