Table 3.

Genes with over 50% of the promoter region CpG sites having higher methylation in tumor tissue from prostate cancer patients with recurrence versus no recurrence

Candidate geneIllumina CpG siteAvg. β value: recurrenceAvg. β value: no recurrencePaCpG locationThird IQR
ABHD9cg183669190.5812640.5224530.000295Island0.649
ABHD9cg260107340.5078420.4429090.000385N_Shore0.565
ABHD9cg174760260.4296700.3578970.000540N_Shore0.525
ABHD9cg173993620.5126390.4322490.000838N_Shore0.614
ABHD9cg084578980.5691490.5182810.001475N_Shore0.643
ABHD9cg161844950.5896350.5301170.001796N_Shore0.672
ABHD9cg158268970.4832900.4345910.002572N_Shore0.535
HOXD3cg133168540.4381430.3641379.46E-06Island0.476
HOXD3cg247041770.4534880.3775732.93E-05Island0.498
HOXD3cg061453360.6710130.5943253.33E-05Island0.742
HOXD3cg010146150.6468530.5751739.87E-05Island0.719
HOXD3cg126345910.4888500.4194120.000159N_Shore0.538
HOXD3cg093877490.6464140.5817650.000419N_Shore0.715
HOXD3cg259388060.4563530.3913040.000618N_Shore0.502
HOXD3cg027730860.6234050.5699830.001001N_Shore0.691
HOXD3cg187021970.4266740.3624980.001237Island0.472

Abbreviation: IQR, interquartile range.

  • aP values with Bonferroni correction for multiple testing within each gene.