Table 2.

Levels of 2-OHE1, 16α-OHE1, and the 2-OHE1:16α-OHE1 ratio by cohort and case–control status, postmenopausal women, the NYUWHS and the NSMSC cohorts (499 cases, 499 controls)

NYUWHSNSMSC
Estrone metaboliteCase (n = 358)Control (n = 358)PCase (n = 141)Control (n = 141)P
2-OHE1, pg/mL
 Median (10th, 90th percentile)150.4 (80.0, 272.0)148.0 (84.0, 269.0)0.34282.5 (221.5, 424.0)284.3 (209.3, 415.5)0.43
16α-OHE1, pg/mL
 Median (10th, 90th percentile)296.0 (188.0, 442.0)286.5 (198.0, 414.0)0.79420.0 (296.3, 534.0)404.0 (275.0, 557.5)0.17
2-OHE1:16α-OHE1 ratio
 Median (10th, 90th percentile)0.51 (0.25, 0.95)0.50 (0.29, 0.89)0.480.70 (0.49, 1.15)0.70 (0.48, 1.18)0.68