Table 1.

Average annual age-adjusted papillary thyroid cancer incidence rates (per 100,000) for 1988–1992 and 2003–2009 and IRR in California, by individual and tumor characteristics

MenWomen
Incidence rateIncidence rate
Na1988–19922003–2009IRRNa1988–19922003–2009IRR
All8,7391.99 (1.88–2.11)3.31 (3.20–3.41)1.66 (1.57–1.77)30,2955.56 (5.39–5.74)11.37 (11.19–11.56)2.04 (1.97–2.12)
Age, y
 <201440.15 (0.10–0.21)0.15 (0.12–0.20)1.04 (0.66–1.66)8210.76 (0.64–0.89)1.00 (0.90–1.11)1.32 (1.08–1.60)
 20–341,5011.42 (1.27–1.59)2.03 (1.87–2.2)1.43 (1.24–1.64)7,4537.12 (6.75–7.50)11.21 (10.81–11.62)1.57 (1.48–1.68)
 35–492,8772.98 (2.71–3.27)4.34 (4.1–4.59)1.45 (1.30–1.62)11,2899.21 (8.74–9.71)18.93 (18.42–19.45)2.05 (1.94–2.18)
 50–642,6363.68 (3.28–4.12)6.81 (6.45–7.19)1.85 (1.63–2.10)7,0357.64 (7.08–8.24)19.06 (18.47–19.67)2.49 (2.30–2.71)
 ≥651,5823.24 (2.82–3.71)3.24 (2.82–3.71)1.99 (1.70–2.32)3,6974.73 (4.30–5.20)12.02 (11.47–12.59)2.54 (2.29–2.82)
Race/ethnicity/nativity
 Non-Hispanic White5,6192.20 (2.06–2.35)3.87 (3.71–4.03)1.75(1.62–1.89)16,5465.80 (5.58–6.03)12.03(11.75–12.32)2.07 (1.98–2.17)
 Non-Hispanic Black2640.83 (0.56–1.18)1.67 (1.37–2.01)2.01 (1.33–3.09)1,0032.78 (2.31–3.31)6.01 (5.49–6.57)2.16 (1.78–2.66)
 Hispanic1,6281.59 (1.32–1.89)2.68 (2.48–2.89)1.69 (1.40–2.06)7,6835.24 (4.83–5.66)11.03 (10.68–11.40)2.11 (1.94–2.30)
  U.S.-bornc4652.02 (1.40–2.85)2.49 (1.98–3.09)1.23 (0.81–1.89)2,2155.48 (4.58–6.52)9.13 (8.22–10.12)1.67 (1.36–2.05)
  Foreign-bornc5111.75 (1.01–3.44)1.90 (1.54–2.32)1.09 (0.74–1.64)2,4755.19 (4.49–5.99)8.43 (7.81–9.09)1.62 (1.38–1.92)
 API1,1342.52 (2.10–3.00)3.54 (3.24–3.85)1.40 (1.15–1.72)4,6827.77 (7.10–8.49)13.03 (12.50–13.57)1.68 (1.52–1.85)
  U.S.-bornc,d1422.23 (1.37–3.53)3.43 (2.68–4.33)1.54 (0.90–2.66)5127.99 (6.33–10.01)12.40 (10.91–14.03)1.55 (1.20–2.02)
  Foreign-bornc,d4912.70 (2.18–3.33)2.66 (2.33–3.04)0.99 (0.77–1.27)2,0577.85 (7.07–8.74)c9.17 (8.62–9.76)1.17 (1.03–1.32)
 Native-Americane230.82 (0.25–1.97)b1.34 (0.67–2.47)1.00 (0.27–5.77)1133.00 (1.62–5.17)6.36 (4.74–8.37)2.12 (1.13–4.21)
Tumor size, cm
 <11,8140.23 (0.19–0.27)0.83 (0.78–0.88)3.66 (3.06–4.40)7,8710.84 (0.78–0.92)3.53 (3.43–3.63)4.18 (3.83–4.57)
 1.0–1.49320.15 (0.12–0.18)0.39 (0.35–0.42)2.56 (2.05–3.22)4,2800.60 (0.55–0.66)1.82 (1.75–1.90)3.03 (2.73–3.37)
 1.5–1.98950.17 (0.14–0.20)0.38 (0.34–0.41)2.22 (1.18–2.76)3,9030.68 (0.62–0.74)1.48 (1.41–1.55)2.17 (1.96–2.41)
 2.0–2.91,4860.30 (0.26–0.35)0.54 (0.50–0.59)1.80 (1.53–2.12)5,7401.08 (1.00–1.15)2.01 (1.94–2.09)1.87 (1.73–2.03)
 3.0–3.99920.20 (0.16–0.23)0.36(0.33–0.40)1.85 (1.51–2.27)2,9000.50 (0.45–0.55)1.02 (0.96–1.07)2.05(1.82–2.32)
 4.0–4.96180.13 (0.10–0.16)0.24 (0.21–0.27)1.84 (1.43–2.39)1,3670.21 (0.17–0.24)0.51 (0.47–0.55)2.46 (2.05–2.97)
 ≥5.08870.16 (0.13–0.19)0.35 (0.31–0.38)2.20 (1.76–2.78)1,3810.23 (0.19–0.27)0.52 (0.48–0.56)2.27 (1.91–2.71)
 Unknown1,1150.66 (0.60–0.73)0.23 (0.20–0.26)0.34 (0.29–0.40)2,8531.43 (1.35–1.52)0.49 (0.45–0.53)0.34 (0.31–0.38)
SEER stage
 Local4,5601.02 (0.94–1.10)1.78 (1.70–1.86)1.75 (1.60–1.92)19,7693.60 (3.46–3.74)7.52 (7.37–7.68)2.09 (2.00–2.18)
 Regional3,2500.75 (0.68–0.82)1.22 (1.16–1.28)1.63 (1.47–1.81)8,6621.60 (1.51–1.69)3.36 (3.26–3.47)2.11 (1.97–2.25)
 Distant7090.17 (0.14–0.21)0.25 (0.22–0.28)1.45 (1.14–1.84)1,2640.22 (0.19–0.26)0.36 (0.33–0.40)1.63 (1.36–1.97)
 Unknown2200.06 (0.04–0.08)0.06 (0.05–0.08)1.06 (0.69–1.65)6000.15 (0.12–0.18)0.12 (0.10–0.14)0.78 (0.66–1.10)
Tumor size/stage
 <2.0 cm/local2,3090.33 (0.29–0.38)1.06 (1.00–1.12)3.20(2.76–3.73)12,0581.57 (1.48–1.67)5.16 (5.04–5.29)3.28 (3.07–3.50)
 <2.0 cm/advancedf1,3130.21 (0.18–0.25)0.53(0.49–0.57)2.49 (2.07–3.02)3,9340.53 (0.48–0.59)1.66 (1.59–1.73)3.11 (2.78–3.48)
 ≥2.0 cm/local1,8630.40 (0.35–0.45)0.66 (0.62–0.71)1.67 (1.45–1.93)6,3061.21 (1.12–1.29)2.14 (2.06–2.22)1.77 (1.64–1.92)
 ≥2.0 cm/advanced2,0880.38 (0.34–0.44)0.82 (0.76–0.87)2.13 (1.84–2.47)4,9810.77 (0.71–0.84)1.89 (1.82–1.97)2.45 (2.23–2.69)
 Unknown/local3880.29 (0.25–0.34)0.06 (0.05–0.08)0.21 (0.15–0.28)1,4050.82 (0.75–0.89)0.22 (0.20–0.25)0.27 (0.24–0.32)
 Unknown/advanced5580.32(0.28–0.37)0.12 (0.10–0.15)0.38(0.30–0.48)1,0110.51 (0.46–0.57)0.18 (0.15–0.20)0.35 (0.29–0.41)
  • a1988–2009.

  • b1988–1997; number of cases was too small to calculate stable rates for the 1988–1992 time period alone.

  • cFor periods 1988–1992 and 1998–2004.

  • dIncludes Chinese, Japanese, Filipino, Vietnamese, Korean, and South Asian persons.

  • eAmerican-Indian/Alaskan Native.

  • fCombines regional and distant stages.