Table 3.

OR for ESD (and 95% CI) from logistic regressions on standardized upper digestive tract microbial richness or on standardized β-diversity metrics

All (333)Stratified by PGI/IIa
Adjusted modelaModel further adjusted for PGI/IIbPGI/II < medianPGI/II ≥ median
OR (95% CI)POR (95% CI)POR (95% CI)POR (95% CI)P
Microbial richness
 Number of genera0.74 (0.58–0.95)0.0180.76 (0.59–0.97)0.0320.63 (0.43–0.89)0.0100.95 (0.66–1.37)0.785
β-diversity
 PC11.45 (1.14–1.85)0.0031.41 (1.10–1.80)0.0061.63 (1.16-2.32)0.0051.19 (0.83–1.69)0.350
 PC21.13 (0.90–1.44)0.2911.15 (0.91 1.45)0.2381.27 (0.91–1.78)0.1661.06 (0.74–1.52)0.758
 PC30.94 (0.74–1.20)0.6340.97 (0.76–1.25)0.8471.01 (0.73–1.41)0.9390.93 (0.66–1.34)0.701

NOTE: Bold indicates P value less than 0.05.

  • aModel adjusted for smoking, gender, age, balloon sampling device, and antibiotic usage in the last 3 months.

  • bModel adjusted for PGI/II besides smoking, gender, age, balloon sampling device, and antibiotic usage in the last 3 months.