Table 2.

Characteristics of the stratified case–cohort study population

LACE (n = 872)Pathways (n = 766)Total (n = 1,638)
Weighted %Weighted %Weighted %P value
Age at breast cancer diagnosis
 <5022.222.922.50.82
 50–6445.246.545.9
 65+32.630.731.5
Race/ethnicity
 White81.666.373.3<0.0001
 Black/AA5.56.76.2
 Hispanic6.210.88.7
 Asian/PI5.512.89.5
 Other1.23.42.4
Education
 Higher secondary or less26.116.420.8<0.0001
 Some college39.639.439.5
 College grad15.225.220.6
 Post-college19.019.019.0
Family history
 No75.780.378.20.12
 Yes24.319.721.8
Smoking history at breast cancer diagnosis
 Never51.952.752.30.92
 Past41.741.541.6
 Current6.45.86.0
Menopausal status at breast cancer diagnosis
 Postmenopausal66.571.869.4<0.0001
 Premenopausal19.428.224.2
 Unknown14.00.06.4
BMI
 Under/normal46.835.340.50.001
 Overweight28.830.729.8
 Obese24.534.129.7
AJCC stage
 I45.751.648.9<0.0001
 II51.537.043.6
 III2.810.46.9
 IV0.01.00.5
Tumor size
 <2 cm62.365.263.90.001
 ≥2 cm37.731.634.4
 Missing0.03.21.7
Number of positive nodes
 065.264.164.60.001
 1–427.024.625.7
 5+7.87.57.6
 Missing0.03.82.1
Tumor grade
 I19.323.521.60.11
 II40.143.542.0
 III–IV31.526.828.9
 Missing9.16.17.5
Breast cancer surgery
 None0.01.30.7<0.0001
 Lumpectomy50.162.556.8
 Mastectomy49.936.342.5
Chemotherapy
 No46.552.649.80.08
 Yes53.547.450.2
Radiation
 No38.766.053.5<0.0001
 Yes61.334.046.5
Hormonal therapy
 No22.627.325.20.06
 Yes77.472.774.8
Any comorbidity (Charlson comorbidity index)
 No87.085.286.00.45
 Yes13.014.814.0
ER status
 Negative18.416.817.50.36
 Positive81.683.282.5
PR status
 Negative35.431.633.30.20
 Positive64.668.466.7
Her2 status
 Negative83.487.085.30.02
 Positive16.613.014.7