Table 2.

Multivariate models with independent predictors of cumulative HPV coinfection

Cumulative coinfection vs. HPV-negative (n = 422)Cumulative coinfection vs. monoinfection (n = 307)
VariableORa (95% CI)ORa (95% CI)
Age at enrollment
 ≤261.001.00
 ≥270.34 (0.17–0.67)0.54 (0.25–1.17)
Number of lifetime sex partners
 0–11.001.00
 2–42.15 (1.14–4.08)1.19 (0.54–2.65)
 ≥53.62 (1.88–6.95)1.22 (0.56–2.66)
Number of new sex partnersb
 01.001.00
 11.33 (0.80–2.21)1.57 (0.85–2.89)
 ≥23.87 (2.16–6.93)2.74 (1.48–5.08)
History of STIsc
 No1.001.00
 Yes2.96 (1.31–6.69)1.06 (0.50–2.24)
HLA-DQB1*06:02
 No1.001.00
 Yes1.83 (1.08–3.09)1.62 (0.90–2.93)
HLA-G*01:01:03
 No1.001.00
 Yes1.12 (0.47–2.71)0.34 (0.14–0.81)
HLA-G*01:01:05
 No1.001.00
 Yes1.06 (0.35–3.21)6.44 (1.66–24.95)

NOTE: Bold indicates statistical significance based on the 95% confidence interval.

  • aMutually adjusted for all other variables in a column.

  • bIn the year before enrollment.

  • cIn lifetime; includes trichomoniasis, chlamydia, herpes, syphilis, gonorrhea, and genital sores.