Table 2.

Characteristics of the SNPs associated with lung cancer risk in Asians

SNPsRegionReported geneLocationA/aN (AA/Aa/aa)MAFCall ratePHWE
rs109374053q28TP63IntronC/T768/622/1270.2890.9740.925
rs1108046618p11.22PIEZO2IntronA/G923/504/650.2120.9580.716
rs13330409p21CDKN2B-AS1IntronT/C738/631/1480.3060.9740.407
rs166368910p14GATA3IntergenicA/G544/710/2600.4060.9720.370
rs21318773q29XXYLT1IntronT/C458/754/3060.4500.9750.984
rs2470085q31IL3-CSF2-P4HA2IntergenicC/T397/750/3700.4910.9740.804
rs27361005p15.33TERTIntronT/G515/757/2440.4110.9740.178
rs28536775p15.33TERTIntronT/C569/741/2070.3810.9740.105
rs28956805q32PPP2R2B-STK32A-DPYSL3IntronT/C743/621/1530.3060.9740.285
rs3660022q12.2MTMR3IntronC/T1246/256/160.0950.9750.492
rs381357215q25.1PSMA45′ near geneA/G998/462/490.1860.9690.668
rs38179636p21.3BTNL2IntronA/G926/518/710.2180.9730.710
rs4016815p15.33CLPTM1LIntronC/T668/681/1680.3350.9740.787
rs44888093q28TP63IntronC/T395/747/3720.4920.9720.610
rs4654985p15.33TERT-CLPTM1LIntronT/C1044/424/510.1730.9760.313
rs46776573q29XXYLT1IntronC/T1101/206/2100.2060.974<0.001
rs46776623q29XXYLT1IntronT/C757/633/1260.2920.9740.886
rs480995720q13CYP24A13′UTRG/A560/704/2530.3990.9740.158
rs649530915q25.1CHRNA35′ near geneC/T476/745/2910.4390.9710.878
rs66728215q25.1CHRNA5IntronT/C477/730/3090.4450.9740.350
rs708680310q25.2VTI1AIntronG/A762/641/1130.2860.9740.178
rs721606417q24.3BPTFIntronA/G633/682/2000.3580.9740.368
rs75395513q12.12TNFRSF19-MIPEPIntergenicT/C755/623/1400.2970.9750.404
rs92723466p21.32HLA-DQA15′ near geneG/A893/112/3330.7090.859<0.001
rs93874786q22.2ROS1-DCBLD1IntergenicC/A390/734/3580.4890.9520.728
rs94395191p36AJAP1-NPHP4IntergenicT/C792/599/1280.2810.9760.941
rs1698839322q12.2MTMR3-HORMAD2-LIFIntergeneT/C1223/279/160.1020.9750.925
rs9524813q29XXYLT1IntronA/Gaaaa

Abbreviation: A/a, major/minor allele; UTR, untranslated region.

  • aData were missing due to genotyping failure.