Table 5.

Early recurrences: comparison of PAM50 and IHC tumor subtype classifications

Early recurrences (n = 243)
N eventsHRLower 95% CIUpper 95% CI
PAM50 subtypea
 LumA61Ref
 LumB822.551.683.88
 HER2-E542.831.834.38
 Basal463.982.476.42
Carey subtype defined by IHCa
 “LumA” surrogate142Ref
 “LumB” surrogate311.190.791.81
 Her2+/ER161.370.782.38
 TNBC542.131.463.11
Adapted by Prat from St. Gallens Consensus conference: subtype defined by IHCb
 “LumA” surrogate69ref
 “LumB” surrogate1041.771.222.56
 Her2+/ER162.051.163.62
 TNBC543.252.224.77
  • aAdjusted for age, race/ethnicity, tumor size, number of positive nodes, and grade.

  • bAdjusted for age, race/ethnicity, tumor size, and number of positive nodes.