Table 3.

Risk of recurrence by PAM50 intrinsic subtype

All recurrences, n = 370Early recurrences (<5 years), n = 243Late recurrences (5–10 years), n = 127
PAM50 subtypeN eventsHRLower 95% CIUpper 95% CIN eventsHRLower 95% CIUpper 95% CIN eventsHRLower 95% CIUpper 95% CI
LumA127Ref61Ref66Ref
LumB1201.941.362.77822.551.683.88381.340.792.28
 LumB Pathways531.540.992.41522.391.483.8610.140.021.08
 LumB LACE672.421.543.82302.931.675.14371.730.993.04
HER2-E671.631.102.41542.831.834.38130.550.281.09
Basal-like562.101.373.22463.982.476.42100.590.281.23
 Basal-like Pathways333.832.336.28335.443.239.150
 Basal-like LACE231.290.752.23132.411.234.75100.630.301.33

NOTE: Adjusted for age, race/ethnicity, tumor size, number of positive nodes, and grade.