Table 1.

Select biomarkers of breast cancer prognosis

MarkerImpactReferences
BCL-2/BAXPromotes cell death10–12
EGFR/HER1Overexpressed in triple-negative tumors13, 38–44
P53Mutation associated with poor prognosis14–24
MIB-1/Ki-67Proliferation index26–35
Cyclin DRegulates cell cycle37, 44–46