Table 2.

Pearson correlations between OPN, PAI-1, PEDF, VEGF, and anthropometric and previously tested serum biomarkers, corrected for multiple testinga

OPN (N = 164)PAI-1 (N = 164)PEDF (N = 164)VEGF (N = 164)
Covariatesrsrsrsrs
OPN−0.040.02−0.02
PAI-1−0.040.46b0.17
PEDF0.020.46b0.11
VEGF−0.020.170.11
Age (y)0.15−0.10−0.12−0.02
BMI (kg/m2)−0.040.36b0.34b0.12
Total bone mineral density (g/cm2)−0.080.230.150.07
Total fat mass (g)−0.020.31b0.37b0.18
Testosterone (pg/mL)−0.0040.230.02−0.01
Estrone (pg/mL)−0.090.250.230.16
Estradiol (pg/mL)−0.160.190.200.19
SHBG (nmol/L)0.29b−0.34b−0.31b−0.05
Free estradiol−0.200.30b0.29b0.19
Free testosterone−0.080.45b0.180.01
Insulin (μU/mL)−0.050.61b0.53b0.05
Leptin (ng/mL)−0.030.33b0.38b0.10
Ghrelin−0.04−0.24−0.230.07
IGF-1−0.250.06−0.00−0.02

NOTE: Significant associations are indicated by superscripts.

  • aBonferroni correction, significant at P = 0.0003.

  • bP < 0.0001.