Table 2.

Postdiagnosis diet quality, risk of death from any cause, and risk of death from breast cancer among 2,317 postmenopausal women diagnosed with invasive breast cancer in the WHI

Poor-quality dietMixed-quality dietBetter-quality diet
Healthy Eating Index-2005 Score Quartile 1 (34–63)Healthy Eating Index-2005 Score Quartile 2 (63–71)Healthy Eating Index-2005 Score Quartile 3 (71–77)Healthy Eating Index-2005 Score Quartile 4 (77–91)Ptrend
N579579580579
Death from any cause (n)11710510291
 Unadjusted HR (95% CI)1.000.84 (0.65–1.09)0.79 (0.61–1.03)0.67 (0.51–0.88)0.004
 Age and energy-adjusted HR (95% CI)1.000.83 (0.64–1.08)0.77 (0.59–1.01)0.63 (0.48–0.83)0.0009
 Multivariate-adjusted HR (95% CI)a1.000.93 (0.71–1.22)0.86 (0.65–1.14)0.74 (0.55–0.99)0.043
Death from breast cancer (n)51484445
 Unadjusted HR (95% CI)1.000.89 (0.60–1.32)0.79 (0.53–1.19)0.78 (0.52–1.17)0.178
 Age and energy-adjusted HR (95% CI)1.000.89 (0.60–1.32)0.79 (0.53–1.19)0.78 (0.52–1.16)0.173
 Multivariate-adjusted HR (95% CI)a1.000.99 (0.66–1.50)0.93 (0.61–1.43)0.91 (0.60–1.40)0.627
Death from causes other than breast cancer (n)66575846
 Unadjusted HR (95% CI)1.000.80 (0.56–1.14)0.79 (0.56–1.13)0.59 (0.40–0.86)0.008
 Age and energy-adjusted HR (95% CI)1.000.79 (0.55–1.12)0.77 (0.54–1.10)0.52 (0.36–0.76)0.001
 Multivariate-adjusted HR (95% CI)a1.000.83 (0.58–1.20)0.79 (0.54–1.15)0.58 (0.38–0.87)0.011
  • aAdjusted for age at screening visit (continuous), WHI component (WHI-DM-intervention, WHI-DM-control, or OS), ethnicity (White non-Hispanic, Black/African American, Hispanic/Latino, other, missing), income (<20,000, 20,000–49,999, ≥50,000, missing), education (high school or below, some college, college, postgraduate, missing), stage (localized, regional, distant, unknown), estrogen receptor status (positive, negative, unknown), progesterone receptor status (positive, negative, unknown), time since diagnosis (continuous), energy intake in kcals (continuous), physical activity in MET-h/wk (0, 0.1–3, 3.1–8.9, 9+, unknown), servings of alcohol per week (continuous), and use of postmenopausal hormone therapy (never, former, current).