High-exposed (n = 47) | Low-exposed (n = 38) | P-value^{f} | |
---|---|---|---|
Age, y^{a} | 69.07 (7.45) | 68.55 (7.93) | 0.75 |
Body mass index (kg/m^{2})^{a} | 27.33 (3.10) | 26.65 (3.04) | 0.31 |
Alcohol intake (units/week)^{a} | 11.48 (13.56) | 17.26 (13.16) | 0.05 |
Smoking status, N (%) | 0.84 | ||
Current smoker | 12 (25.5%) | 8 (21.1%) | |
Former smoker | 28 (59.6) | 23 (60.5%) | |
Never smoker | 7 (14.9%) | 7 (18.4%) | |
Skin cancer, N (%) | 4 (8.5%) | 3 (7.9%) | 0.92 |
Infectious disease in the past 4 weeks, N (%) | 4 (8.7%) | 4 (10.5%) | 0.78 |
Chronic disease, N (%)^{b} | 24 (51.1%) | 20 (52.6%) | 0.89 |
Chronic inflammatory disease, N (%)^{c} | 13 (27.7%) | 11 (28.9%) | 0.90 |
Medication, N (%) | 0.33 | ||
Immunosuppressant | 5 (10.6%) | 4 (10.5%) | |
NSAIDs | 14 (29.8%) | 6 (15.8%) | |
Antibiotics | 0 | 1 (2.6%) | |
TCDD_{current} (ppt)^{d} | 3.25 (7.43) | 1.07 (6.42) | 0.002 |
TCDD_{max} (ppt)^{e} | 79.82 (33.28) | 7.53 (32.14) | 0.001 |
Abbreviation: NSAIDs, nonsteroidal anti-inflammatory drugs.
↵^{a}Mean (SD).
↵^{b}Chronic diseases included: diabetes, coronary heart disease, and hypertension.
↵^{c}Chronic inflammatory diseases: chronic obstructive pulmonary disease, psoriasis, sarcoidosis, asthmatic bronchitis, rheumatoid arthritis, liver failure, Crohn's disease, fibromyalgia, and allergy.
↵^{d}Current levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD_{current}) parts per trillion, geometric mean (geometric standard deviation).
↵^{e}Estimated maximum levels of TCDD (TCDD_{max}) parts per trillion, geometric mean (geometric standard deviation).
↵^{f}P values from t tests for continuous variables and χ^{2} tests for categorical variables.