Table 3.

Characteristics of cancer prognostic tools

FeaturesAdjuvantaAJCCANNaBioChemicalCancerMathaCapraa
Outcomes
 Overall survival/mortality
  Cancer-specific+b+++b
  Noncancer-specific++
 DFS/PFS++b++*+
 Clinical response
 Therapy-induced side effects
Cancer characteristics++++++
Demographic characteristics+++++
Comorbidities+
Therapy impact+++b
Genetic factors+
Modifiable factors
Patient user recommendedNDND+
Data sourceMixedClinicClinicClinicMixedClinic
Validation++++++
FunderAstra Zeneca The Greenberg Breast Cancer FoundationNDIDEA, ANNs, NCINDNDUCSF
Modality
 Web-based++++++
 Other modality+b
UpdatedJune 2006NDOctober 20072011April 20092010
FeaturesCSQSEBRTFinProgGBMHan
Outcomes
 Overall survival/mortality
  Cancer-specific+++
  Noncancer-specific+
 DFS/PFS+++
 Clinical response
 Therapy-induced side effects
Cancer characteristics++++
Demographic characteristics+++
Comorbidities++
Therapy impact++++b
Genetic factors+
Modifiable factors
Patient user recommended+
Data sourcePopulationClinicPopulationClinicClinic
Validation+++++
FunderNCINDHelsinki University Research Funds, the Academy of Finland, the Cancer Society of FinlandNDND
Modality
 Web-based++c+++
 Other modality
Updated2010NDNDND2011
FeaturesIBTRKCIaLerneraMAASTROaMD AndersonaMSKa
Outcomes
 Overall survival/mortality
  Cancer-specific++b+b+b+b
  Noncancer-specific
 DFS/PFS++b+b+b+b
 Clinical response+b+b
 Therapy-induced side effects+b
Cancer characteristics+++++b+
Demographic characteristics+++b+b+b+b
Comorbidities+b+b+b
Therapy impact++b+b+b+b
Genetic factors+
Modifiable factors
Patient user recommended+
Data sourceClinicPopulationbMixedbClinicClinicPopulationbClinicbClinic
Validation++b+++b+
FunderNDKnight Cancer InstituteNDNDNDND
Modality
 Web-based++++++b
 Other modality+b
UpdatedNDNDNDJuly 2011NDND
FeaturesNomogramsaNumeracyPrognostigramQxMDRoswell Park
Outcomes
 Overall survival/mortality
  Cancer-specific+b+b++b+
  Noncancer-specific+b
 DFS/PFS+b++b
 Clinical response
 Therapy-induced side effects
Cancer characteristics+b++++
Demographic characteristics+b+b++b
Comorbidities+++b
Therapy impact+b+b+
Genetic factors+
Modifiable factors+
Patient user recommended+ND
Data sourcePopulationbClinicbClinicMixedClinicbMixed
Validation+b++ND+
FunderUniversity of MontrealNDNDNDND
Modality
 Web-based++++
 Other modality+
UpdatedNDAugust 2011NDDecember 2011ND

Abbreviations: Mixed, used a combination of clinic and population-based sample; ND, not defined.

  • aIndicates multiple calculators for cancer sites in the tool.

  • bIndicates that at least one but not all calculators has the feature.

  • cExcel version downloadable.