Table 3.

Risk of multiple myeloma associated with alcohol consumption in pooled study population by various factors

CaseControlOR (95% CI)a,bCaseControlOR (95% CI)a,bPinteraction
Study design
Alcohol statusHospitalPopulation
Never drinker1288101.00 (–)49115701.00 (–)
Ever drinker1971,1480.90 (0.68–1.18)73936870.73 (0.63–0.84)0.01
 Current796370.76 (0.54–1.07)38023450.53 (0.45–0.63)
  Currentc916660.81 (0.58–1.14)42423840.60 (0.51–0.71)
 Former311661.04 (0.66–1.64)2175471.21 (0.99–1.48)
  Formerd191560.79 (0.45–1.37)1735081.02 (0.82–1.27)
Smoking status
Ever smokerNever smoker
Never drinker2078491.00 (–)41215281.00 (–)
Ever drinker5763,2230.74 (0.61–0.89)35616110.84 (0.70–1.01)0.50
 Current2782,0170.53 (0.43–0.66)1799650.65 (0.52–0.81)
  Currentc3152,0700.61 (0.49–0.76)1979800.71 (0.57–0.88)
 Former1615121.16 (0.90–1.50)862011.34 (1.00–1.80)
  Formerd1244590.95 (0.72–1.26)681861.10 (0.80–1.51)
BMI
BMI <25 kg/m2BMI ≥ 25 kg/m2
Never drinker2178811.00 (–)31811491.00 (–)
Ever drinker3201,3820.79 (0.64–0.98)39220230.73 (0.60–0.88)0.77
 Current1431,1060.54 (0.41–0.69)16410140.57 (0.45–0.72)
  Currentc1691,1360.62 (0.48–0.79)19310510.66 (0.52–0.83)
 Former1093091.38 (1.03–1.84)1343801.10 (0.86–1.42)
  Formerd832791.11 (0.80–1.52)1053430.94 (0.71–1.24)
  • aAdjusted for sex, age, race, and center.

  • bReference group is never drinkers.

  • cIncludes participants who ceased drinking within 2 years before completion of questionnaire.

  • dExcludes participants who ceased drinking within 2 years before completion of questionnaire.